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. 1981 May;19(5):937–939. doi: 10.1128/aac.19.5.937

Effect of Acyclovir on Latent Herpes Simplex Virus Infections in Trigeminal Ganglia of Mice†

Richard J Klein 1, Eugene DeStefano 1, Alvin E Friedman-kien 1,2, Eileen Brady 2
PMCID: PMC181548  PMID: 6271054

Abstract

The inhibition by acyclovir of the in vitro reactivation of herpes simplex virus from latently infected ganglion explant cultures is dependent on the continuous presence of this drug. Administration of acyclovir subcutaneously, orally, or by continuous perfusion to mice with established latent infections did not eliminate latent virus from the trigeminal ganglia.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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