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. 1981 Sep;20(3):410–414. doi: 10.1128/aac.20.3.410

Metronidazole Metabolism in Cultures of Entamoeba histolytica and Trichomonas vaginalis

Bernard B Beaulieu Jr †, Martha A McLafferty †, Ronald L Koch †, Peter Goldman *
PMCID: PMC181711  PMID: 6272633

Abstract

Acetamide forms from metronidazole in cultures of either Entamoeba histolytica or Trichomonas vaginalis as it does in cultures of bacteria which are susceptible to this drug. Under aerobic conditions, the formation of acetamide is more rapid in a strain of T. vaginalis which is more susceptible to metronidazole. Thus, it appears that the formation of acetamide may be associated with the microbiocidal action of metronidazole.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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