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Canadian Medical Association Journal logoLink to Canadian Medical Association Journal
. 1978 Feb 18;118(4):369–372.

Selection of operation in patients with bleeding esophageal varices.

B Langer, S C Patel, R M Stone, R F Colapinto, M J Phillips, M M Fisher
PMCID: PMC1817958  PMID: 305280

Abstract

The results of surgical treatment of bleeding esophageal varices over an 8-year period in 155 patients are reviewed. Primary treatment of bleeding was conservative, with intravenous administration of vasopressin and balloon tamponade. Emergency operations were carried out after 48 hours in persons with persistent bleeding who were surgical candidates. Operative mortality was higher in this group (40%) than in those undergoing elective or urgent operations (each 10%). Postoperative encephalopathy occurred in 35% of patients and was correlated closely to late death after establishment of a shunt. The mesocaval shunt is no better than the portacaval but appears to be a good alternative in an emergency. In a controlled trial the distal splenorenal shunt was found to be associated with a lower rate of postoperative encephalopathy than the portacaval shunt, but thus far the long-term survival rates have not differed.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Drapanas T., LoCicero J., 3rd, Dowling J. B. Hemodynamics of the interposition mesocaval shunt. Ann Surg. 1975 May;181(5):523–533. doi: 10.1097/00000658-197505000-00004. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Edmondson H. T., Jackson F. C., Juler G. L., Sigel B., Perrin E. B. Clinical investigation of the portacaval shunt. IV. A report of early survival from the emergency operation. Ann Surg. 1971 Mar;173(3):372–380. doi: 10.1097/00000658-197103000-00007. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Galambos J. T., Warren W. D., Rudman D., Smith R. B., 3rd, Salam A. A. Selective and total shunts in the treatment of bleeding varices. A randomized controlled trial. N Engl J Med. 1976 Nov 11;295(20):1089–1095. doi: 10.1056/NEJM197611112952001. [DOI] [PubMed] [Google Scholar]
  4. Jackson F. C., Perrin E. B., Felix W. R., Smith A. G. A clinical investigation of the portacaval shunt. V. Survival analysis of the therapeutic operation. Ann Surg. 1971 Oct;174(4):672–701. doi: 10.1097/00000658-197110000-00012. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Mikkelsen W. P., Edmondson H. A., Peters R. L., Redeker A. G., Reynolds T. B. Extra- and intrahepatic portal hypertension without cirrhosis (hepatoportal sclerosis). Ann Surg. 1965 Oct;162(4):602–620. doi: 10.1097/00000658-196510000-00006. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Orloff M. J. Emergency portacaval shunt: a comparative study of shunt, varix ligation and nonsurgical treatment of bleeding esophageal varices in unselected patients with cirrhosis. Ann Surg. 1967 Sep;166(3):456–478. doi: 10.1097/00000658-196709000-00012. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Reichle F. A., Siplet H., Tomasello P. A., Alfonso A., Reichle R. M., Essa N., Rosemond G. P. Effect of end-to-side and side-to-side portacaval shunt on liver function. Am J Gastroenterol. 1973 Aug;60(2):114–121. [PubMed] [Google Scholar]
  8. Resnick R. H., Chalmers T. C., Ishihara A. M., Garceau A. J., Callow A. D., Schimmel E. M., O'Hara E. T. A controlled study of the prophylactic portacaval shunt. A final report. Ann Intern Med. 1969 Apr;70(4):675–688. doi: 10.7326/0003-4819-70-4-675. [DOI] [PubMed] [Google Scholar]
  9. Resnick R. H., Iber F. L., Ishihara A. M., Chalmers T. C., Zimmerman H. A controlled study of the therapeutic portacaval shunt. Gastroenterology. 1974 Nov;67(5):843–857. [PubMed] [Google Scholar]
  10. Warren W. D., Zeppa R., Fomon J. J. Selective trans-splenic decompression of gastroesophageal varices by distal splenorenal shunt. Ann Surg. 1967 Sep;166(3):437–455. doi: 10.1097/00000658-196709000-00011. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Whipple A. O. The Problem of Portal Hypertension in Relation to the Hepatosplenopathies. Ann Surg. 1945 Oct;122(4):449–475. doi: 10.1097/00000658-194510000-00001. [DOI] [PMC free article] [PubMed] [Google Scholar]

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