Skip to main content
Canadian Medical Association Journal logoLink to Canadian Medical Association Journal
. 1978 Apr 8;118(7):807–810.

The nonspecific nature of fibrin thrombi in ischemic bowel disease.

A H Qizilbash
PMCID: PMC1818174  PMID: 638912

Abstract

Twenty cases of ischemic bowel disease were analysed to determine the frequency and significance of fibrin thrombi in this condition. Fibrin thrombi were present in all 10 patients with occlusive ischemic bowel disease and in 7 of the 10 patients with nonocclusive ischemic bowel disease. In addition, fibrin thrombi were noted in a wide variety of specific and nonspecific inflammatory bowel diseases and in acute appendicitis. We conclude that fibrin thrombi are a nonspecific feature of tissue necrosis and that their mere presence in the bowel should not be regarded as an expression of disseminated intravascular coagulation.

Full text

PDF
807

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bogomoletz W. V. Fibrin thrombi, a cause of clindamycin-associated colitis? Gut. 1976 Jun;17(6):483–487. doi: 10.1136/gut.17.6.483. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Brandt L. J., Gomery P., Mitsudo S. M., Chandler P., Boley S. J. Disseminated intravascular coagulation in nonocclusive mesenteric ischemia: the lack of specificity of fibrin thrombi in intestinal infarction. Gastroenterology. 1976 Dec;71(6):954–957. [PubMed] [Google Scholar]
  3. Castelli M. F., Qizilbash A. H., Fyshe T. G. Ischemic bowel disease. Can Med Assoc J. 1974 Nov 2;111(9):935-6, 939-41. [PMC free article] [PubMed] [Google Scholar]
  4. LENDRUM A. C., FRASER D. S., SLIDDERS W., HENDERSON R. Studies on the character and staining of fibrin. J Clin Pathol. 1962 Sep;15:401–413. doi: 10.1136/jcp.15.5.401. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Margaretten W., McKay D. G. Thrombotic ulcerations of the gastrointestinal tract. Arch Intern Med. 1971 Feb;127(2):250–253. [PubMed] [Google Scholar]
  6. Marston A., Pheils M. T., Thomas M. L., Morson B. C. Ischaemic colitis. Gut. 1966 Feb;7(1):1–15. doi: 10.1136/gut.7.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. McGovern V. J., Goulston S. J. Ischaemic enterocolitis. Gut. 1965 Jun;6(3):213–220. doi: 10.1136/gut.6.3.213. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Whitehead R. Ischaemic enterocolitis: an expression of the intravascular coagulation syndrome. Gut. 1971 Nov;12(11):912–917. doi: 10.1136/gut.12.11.912. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Canadian Medical Association Journal are provided here courtesy of Canadian Medical Association

RESOURCES