Abstract
The association of bone lesions, polyarthritis and cutaneous nodules with pancreatic disease is being recognized and reported more frequently. In adults all forms of pancreatitis and carcinoma of the pancreas have been involved, but in the few children described these complications have been associated with acute traumatic pancreatitis. This paper describes two cases of acute traumatic pancreatitis in which polyarthritis and limb pains were noted after 2 to 3 weeks. In one child osteolytic lesions and periostitis were seen on roentgenograms 7 weeks after the onset of pancreatitis. In the other child minor roentgenographic changes were not seen until 5 months after the onset; however, bone scans showed clear-cut abnormalities after 1 month. Almost complete resolution could be expected within a year. Serum lipase and amylase concentrations remained elevated during the acute illness. Disseminated fat necrosis is apparently related to the excess amounts of circulating lipase.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Achord J. L., Gerle R. D. Bone lesions in pancreatitis. Am J Dig Dis. 1966 Jun;11(6):453–460. doi: 10.1007/BF02233604. [DOI] [PubMed] [Google Scholar]
- Boswell S. H., Baylin G. J. Metastatic fat necrosis and lytic bone lesions in a patient with painless acute pancreatitis. Radiology. 1973 Jan;106(1):85–86. doi: 10.1148/106.1.85. [DOI] [PubMed] [Google Scholar]
- GERLE R. D., WALKER L. A., ACHORD J. L., WEENS H. S. OSSEOUS CHANGES IN CHRONIC PANCREATITIS. Radiology. 1965 Aug;85:330–337. doi: 10.1148/85.2.330. [DOI] [PubMed] [Google Scholar]
- IMMELMAN E. J., BANK S., KRIGE H., MARKS I. N. ROENTGENOLOGIC AND CLINICAL FEATURES OF INTRAMEDULLARY FAT NECROSIS IN BONES IN ACUTE AND CHRONIC PANCREATITIS. Am J Med. 1964 Jan;36:96–105. doi: 10.1016/0002-9343(64)90152-4. [DOI] [PubMed] [Google Scholar]
- KUSHNER D. S., SZANTO P. B. Fulminant polyarthritis, fever, and cutaneous nodules in an alcoholic patient. J Am Med Assoc. 1958 Jul 26;167(13):1625–1632. [PubMed] [Google Scholar]
- Keating J. P., Shackelford G. D., Shackelford P. G., Ternberg J. L. Pancreatitis and osteolytic lesions. J Pediatr. 1972 Aug;81(2):350–353. doi: 10.1016/s0022-3476(72)80311-1. [DOI] [PubMed] [Google Scholar]
- Keeney R. E. Letter: Enlarging on the child abuse injury spectrum. Am J Dis Child. 1976 Aug;130(8):902–902. doi: 10.1001/archpedi.1976.02120090112025. [DOI] [PubMed] [Google Scholar]
- Moore S. Syndromes resulting from dissemination of pancreatic enzymes. J Rheumatol. 1975 Mar;2(1):5–6. [PubMed] [Google Scholar]
- Neuer F. S., Roberts F. F., McCarthy V. Osteolytic lesions following traumatic pancreatitis. Am J Dis Child. 1977 Jul;131(7):738–740. doi: 10.1001/archpedi.1977.02120200020005. [DOI] [PubMed] [Google Scholar]
- Schrier R. W., Melmon K. L., Fenster L. F. Subcutaneous nodular fat necrosis in pancreatitis. Arch Intern Med. 1965 Dec;116(6):832–836. [PubMed] [Google Scholar]
- Slovis T. L., Berdon W. E., Haller J. O., Baker D. H., Rosen L. Pancreatitis and the battered child syndrome. Report of 2 cases with skeletal involvement. Am J Roentgenol Radium Ther Nucl Med. 1975 Oct;125(2):456–461. doi: 10.2214/ajr.125.2.456. [DOI] [PubMed] [Google Scholar]
- Sperling M. A. Bone lesions in pancreatitis. Australas Ann Med. 1968 Nov;17(4):334–340. doi: 10.1111/imj.1968.17.4.334. [DOI] [PubMed] [Google Scholar]