Skip to main content
PMC home page
Canadian Medical Association Journal logoLink to Canadian Medical Association Journal
. 1978 Jun 10;118(11):1395–1398.

Use of a topical antibiotic spray in vaginal surgery.

V C Wright, N M Lanning, R Natale
PMCID: PMC1818395  PMID: 657032

Abstract

During vaginal hysterectomy with or without colporrhaphy a topical aerosol spray containing neomycin sulfate, polymyxin B sulfate and zinc bacitracin was used in 50 patients to decrease the change of postoperative pelvic infection; a placebo spray was used in another 50 patients. All patients were treated preoperatively with povidone iodine and postoperatively with nitrofurantoin and an antibacterial irrigating solution for the bladder if catheter drainage was necessary. The frequency of postoperative pelvic infection was 16% in the group sprayed with the antibiotic combination and 34% in the group sprayed with the placebo, a significant difference (P less than 0.05).

Full text

PDF
1395

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Allen J. L., Rampone J. F., Wheeless C. R. Use of a prophylactic antibiotic in elective major gynecologic operations. Obstet Gynecol. 1972 Feb;39(2):218–224. [PubMed] [Google Scholar]
  2. Black W. A., Hatch L. A. Increasing sensitivity rates of urinary gram-negative bacilli to antimicrobials. J Urol. 1973 Sep;110(3):336–338. doi: 10.1016/s0022-5347(17)60208-8. [DOI] [PubMed] [Google Scholar]
  3. Bolling D. R., Jr, Plunkett G. D. Prophylactic antibiotics for vaginal hysterectomies. Obstet Gynecol. 1973 May;41(5):689–692. [PubMed] [Google Scholar]
  4. Breeden J. T., Mayo J. E. Low dose prophylactic antibiotics in vaginal hysterectomy. Obstet Gynecol. 1974 Mar;43(3):379–385. [PubMed] [Google Scholar]
  5. COPENHAVER E. H. HYSTERECTOMY: VAGINAL VERSUS ABDOMINAL. Surg Clin North Am. 1965 Jun;45:751–763. doi: 10.1016/s0039-6109(16)37598-3. [DOI] [PubMed] [Google Scholar]
  6. Chehab H. E. Decreasing the morbidity of vaginal hysterectomy. Obstet Gynecol. 1968 Feb;31(2):198–207. doi: 10.1097/00006250-196802000-00008. [DOI] [PubMed] [Google Scholar]
  7. FLEMING S. P., KEARNS P. R., LOCK F. R. Factors influencing morbidity following vaginal hysterectomy. Obstet Gynecol. 1954 Sep;4(3):295–301. [PubMed] [Google Scholar]
  8. Frymire L. J. Comparison of suprapubic versus Foley drains. Obstet Gynecol. 1971 Aug;38(2):239–244. [PubMed] [Google Scholar]
  9. GRIMES H. G., GEIGER C. J. Furacin (nitrofurazone) vaginal suppositories in operative gynecology: a clinical and bacteriologic study of 137 patients. Am J Obstet Gynecol. 1960 Mar;79:441–450. doi: 10.1016/0002-9378(60)90241-6. [DOI] [PubMed] [Google Scholar]
  10. Glover M. W., van Nagell J. R., Jr The effect of prophylactic ampicillin on pelvic infection following vaginal hysterectomy. Am J Obstet Gynecol. 1976 Oct 1;126(3):385–388. doi: 10.1016/0002-9378(76)90555-x. [DOI] [PubMed] [Google Scholar]
  11. Goosenberg J., Emich J. P., Jr, Schwarz R. H. Prophylactic antibiotics in vaginal hysterectomy. Am J Obstet Gynecol. 1969 Oct 15;105(4):503–506. [PubMed] [Google Scholar]
  12. Grossman J. H., 3rd, Adams R. L., Hierholzer W. J., Jr Epidemiologic surveillance during a clinical trial of antibiotic prophylaxis in pelvic surgery. Am J Obstet Gynecol. 1977 Jul 15;128(6):690–692. doi: 10.1016/0002-9378(77)90222-8. [DOI] [PubMed] [Google Scholar]
  13. Harralson J. D., van Nagell J. R., Jr, Roddick J. W., Jr, Sprague A. D. The effect of prophylactic antibiotics on pelvic infection following vaginal hysterectomy. Am J Obstet Gynecol. 1974 Dec 15;120(8):1046–1049. doi: 10.1016/0002-9378(74)90148-3. [DOI] [PubMed] [Google Scholar]
  14. Jackson G. W. Suprapubic postoperative bladder drainage. A report of 50 cases. Am J Obstet Gynecol. 1969 Sep 1;105(1):59–63. doi: 10.1016/0002-9378(69)90156-2. [DOI] [PubMed] [Google Scholar]
  15. Johnson C. G. Vaginal hysterectomy and vaginectomy in personal retrospect. Am J Obstet Gynecol. 1969 Sep 1;105(1):14–19. doi: 10.1016/0002-9378(69)90149-5. [DOI] [PubMed] [Google Scholar]
  16. Ledge W. J. Infections in obstetrics and gynecology. New developments in treatment. Surg Clin North Am. 1972 Dec;52(6):1447–1458. [PubMed] [Google Scholar]
  17. Ledger W. J., Sweet R. L., Headington J. T. Prophylactic cephaloridine in the prevention of postoperative pelvic infections in premenopausal women undergoing vaginal hysterectomy. Am J Obstet Gynecol. 1973 Mar 15;115(6):766–774. doi: 10.1016/0002-9378(73)90518-8. [DOI] [PubMed] [Google Scholar]
  18. Moro M., Andrews M. Prophylactic antibiotics in cesarean section. Obstet Gynecol. 1974 Nov;44(5):688–692. [PubMed] [Google Scholar]
  19. Neely M. R. Reducing the morbidity of vaginal hysterectomy. J Obstet Gynaecol Br Commonw. 1969 Feb;76(2):176–177. doi: 10.1111/j.1471-0528.1969.tb05816.x. [DOI] [PubMed] [Google Scholar]
  20. PRATT J. H., SCHERMAN Q. Morbidity in vaginal hysterectomy. Am J Obstet Gynecol. 1954 Jun;67(6):1323–1337. doi: 10.1016/s0002-9378(16)38500-3. [DOI] [PubMed] [Google Scholar]
  21. Pratt J. H., Galloway J. R. Vaginal hysterectomy in patients less than 36 or more than 60 years of age. Am J Obstet Gynecol. 1965 Nov 15;93(6):812–821. doi: 10.1016/0002-9378(65)90082-7. [DOI] [PubMed] [Google Scholar]
  22. TAYLOR E. S., HANSEN R. R. Morbidity following vaginal hysterectomy and colpoplasty. Obstet Gynecol. 1961 Mar;17:346–348. [PubMed] [Google Scholar]
  23. White S. C., Wartel J., Wade M. E. Comparison of abdominal and vaginal hysterectomies. A review of 600 operations. Obstet Gynecol. 1971 Apr;37(4):530–537. [PubMed] [Google Scholar]

Articles from Canadian Medical Association Journal are provided here courtesy of Canadian Medical Association

RESOURCES