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. 1982 Jan;21(1):146–150. doi: 10.1128/aac.21.1.146

Effect of acyclovir and interferon on human hematopoietic progenitor cells.

L M Parker, J M Lipton, N Binder, E L Crawford, M Kudisch, M J Levin
PMCID: PMC181843  PMID: 6177284

Abstract

Continuous in vitro exposure of human bone marrow cells to acyclovir (approximately 200 microM) or human leukocyte interferon (approximately 250 U/ml) caused 50% inhibition of granulocyte colony-forming cell differentiation. Colonies expressed in the presence of either agent were reduced both in size and number. Erythroid progenitors were more resistant than granulocyte progenitors to the antiproliferative effects of acyclovir. Progenitor cells of patients recovering from cytotoxic chemotherapy were no more sensitive to the effects of acyclovir or interferon than were cells obtained from patients before chemotherapy.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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