Skip to main content
NCBI home page
Antimicrobial Agents and Chemotherapy logoLink to Antimicrobial Agents and Chemotherapy
. 1982 Feb;21(2):339–340. doi: 10.1128/aac.21.2.339

Lack of in vitro activity of cefoxitin, cefamandole, cefuroxime, and piperacillin against Chlamydia trachomatis.

W R Bowie
PMCID: PMC181884  PMID: 6462108

Abstract

Newer penicillins and cephalosporins are being evaluated in many infections. One of these infections, acute pelvic inflammatory disease, can be caused by Chlamydia trachomatis. This study demonstrated that cefoxitin, cefamandole, cefuroxime, and piperacillin had no effective in vitro activity against C. trachomatis.

Full text

PDF
339

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bowie W. R., Floyd J. F., Miller Y., Alexander E. R., Holmes J., Holmes K. K. Differential response of chlamydial and ureaplasma-associated urethritis to sulphafurazole (sulfisoxazole) and aminocyclitols. Lancet. 1976 Dec 11;2(7998):1276–1278. doi: 10.1016/s0140-6736(76)92034-1. [DOI] [PubMed] [Google Scholar]
  2. Bowie W. R., Lee C. K., Alexander E. R. Prediction of efficacy of antimicrobial agents in treatment of infections due to Chlamydia trachomatis. J Infect Dis. 1978 Nov;138(5):655–659. doi: 10.1093/infdis/138.5.655. [DOI] [PubMed] [Google Scholar]
  3. Cevenini R., Landini M. P., Donati M., Rumpianesi F. Antimicrobial drug susceptibility of 15 strains of Chlamydia trachomatis recently isolated from cases of non-gonococcal urethritis, in Italy. J Antimicrob Chemother. 1980 Mar;6(2):294–296. doi: 10.1093/jac/6.2.294. [DOI] [PubMed] [Google Scholar]
  4. Coufalik E. D., Taylor-Robinson D., Csonka G. W. Treatment of nongonococcal urethritis with rifampicin as a means of defining the role of Ureaplasma urealyticum. Br J Vener Dis. 1979 Feb;55(1):36–43. doi: 10.1136/sti.55.1.36. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Cunningham F. G., Gilstrap L. C., 3rd, Kappus S. S. Treatment of obstetric and gynecologic infections with cefamandole. Am J Obstet Gynecol. 1979 Mar 15;133(6):602–610. doi: 10.1016/0002-9378(79)90005-x. [DOI] [PubMed] [Google Scholar]
  6. Holmes K. K., Eschenbach D. A., Knapp J. S. Salpingitis: overview of etiology and epidemiology. Am J Obstet Gynecol. 1980 Dec 1;138(7 Pt 2):893–900. doi: 10.1016/0002-9378(80)91078-9. [DOI] [PubMed] [Google Scholar]
  7. Keshishyan H., Hanna L., Jawetz E. Emergence of rifampin-resistance in Chlamydia trachomatis. Nature. 1973 Jul 20;244(5412):173–174. doi: 10.1038/244173a0. [DOI] [PubMed] [Google Scholar]
  8. Lee C. K., Bowie W. R., Alexander E. R. In vitro assays of the efficacy of antimicrobial agents in controlling Chlamydia trachomatis propagation. Antimicrob Agents Chemother. 1978 Mar;13(3):441–445. doi: 10.1128/aac.13.3.441. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Mourad A., Sweet R. L., Sugg N., Schachter J. Relative resistance to erythromycin in Chlamydia trachomatis. Antimicrob Agents Chemother. 1980 Nov;18(5):696–698. doi: 10.1128/aac.18.5.696. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Ridgway G. L., Oriel J. D. Activity of antimicrobials against Chlamydia trachomatis in vitro. J Antimicrob Chemother. 1979 Jul;5(4):483–484. doi: 10.1093/jac/5.4.483. [DOI] [PubMed] [Google Scholar]
  11. Sweet R. L., Ledger W. J. Cefoxitin: single-agent treatment of mixed aerobic-anaerobic pelvic infections. Obstet Gynecol. 1979 Aug;54(2):193–198. [PubMed] [Google Scholar]

Articles from Antimicrobial Agents and Chemotherapy are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES