Abstract
The minimal inhibitory and bactericidal concentrations for 108 group B streptococcal strains were determined for two new cephalosporins, cefonicid and ceftizoxime, and compared to those of penicillin G. Penicillin G was the most active inhibitory and bactericidal agent. Ceftizoxime was a significantly more active inhibitory and bactericidal agent than cefonicid (P less than 0.0005, P less than 0.025, respectively.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Allen J. L., Sprunt K. Discrepancy between minimum inhibitory and minimum bactericidal concentrations of penicillin for group A and group B beta-hemolytic streptococci. J Pediatr. 1978 Jul;93(1):69–71. doi: 10.1016/s0022-3476(78)80603-9. [DOI] [PubMed] [Google Scholar]
- Baker C. J., Webb B. J., Barrett F. F. Antimicrobial susceptibility of group B streptococci isolated from a variety of clinical sources. Antimicrob Agents Chemother. 1976 Jul;10(1):128–131. doi: 10.1128/aac.10.1.128. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dorand R. D., Adams G. Relapse during penicillin treatment of group B streptococcal meningitis. J Pediatr. 1976 Aug;89(2):188–190. doi: 10.1016/s0022-3476(76)80444-1. [DOI] [PubMed] [Google Scholar]
- Ferrieri P., Burke B., Nelson J. Production of bacteremia and meningitis in infant rats with group B streptococcal serotypes. Infect Immun. 1980 Mar;27(3):1023–1032. doi: 10.1128/iai.27.3.1023-1032.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Howes V. J., Mitchell R. G. Meningitis due to relatively penicillin-resistant pneumococcus. Br Med J. 1976 Apr 24;1(6016):996–996. doi: 10.1136/bmj.1.6016.996. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kim K. S., Anthony B. F. Importance of bacterial growth phase in determining minimal bactericidal concentrations of penicillin and methicillin. Antimicrob Agents Chemother. 1981 Jun;19(6):1075–1077. doi: 10.1128/aac.19.6.1075. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kim K. S., Anthony B. F. Penicillin tolerance in group B streptococci isolated from infected neonates. J Infect Dis. 1981 Nov;144(5):411–419. doi: 10.1093/infdis/144.5.411. [DOI] [PubMed] [Google Scholar]
- Schaad U. B., McCracken G. H., Jr, Loock C. A., Thomas M. L. Pharmacokinetics and bacteriologic efficacy of moxalactam, cefotaxime, cefoperazone, and rocephin in experimental bacterial meningitis. J Infect Dis. 1981 Feb;143(2):156–163. doi: 10.1093/infdis/143.2.156. [DOI] [PubMed] [Google Scholar]
- Summary of the workshop on perinatal infections due to group B Streptococcus. J Infect Dis. 1977 Jul;136(1):137–152. doi: 10.1093/infdis/136.1.137. [DOI] [PubMed] [Google Scholar]