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. 1979 Apr 21;120(8):951–956.

L'intoxication par antidépresseurs tricycliques chez l'enfant et l'adolescent.

Poisoning due to tricyclic antidepressants in children and adolescents

P Rollin, A J Antaki
PMCID: PMC1819262  PMID: 373877

Abstract

During the last decade there has been a substantial increase in the number of poisonings due to tricyclic antidepressants in both children and adults. The main toxic manifestations are of anticholinergic origin, and the most frequent constitute the so-called central anticholinergic syndrome. Most of the deaths result from the cardiac complications. Three cases are presented that illustrate chiefly the toxic manifestations related to the central nervous system. The therapeutic management is reviewed in the light of the metabolism of the tricyclic antidepressants, their pharmacologic action and the mechanism of their toxic effects.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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