Abstract
The stability of cephapirin, gentamicin, penicillin G, nafcillin, ticarcillin, and vancomycin was tested in peritoneal dialysate at 25 degrees C for 24 h. All of the antimicrobial agents were stable except penicillin G, which lost 25% of activity over 24 h (P less than 0.01). The once-daily preparation of drug-dialysate solution is feasible for the treatment of peritonitis in patients on continuous ambulatory peritoneal dialysis.
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Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Flynn C. T., Shadur C. A. A comparison of continuous ambulatory peritoneal dialysis in diabetic and nondiabetic patients. Am J Kidney Dis. 1981 Jul;1(1):15–23. doi: 10.1016/s0272-6386(81)80006-6. [DOI] [PubMed] [Google Scholar]
- Mann J. M., Coleman D. L., Boylan J. C. Stability of parenteral solutions of sodium cephalothin, cephaloridine, potassium penicillin G (buffered) and vancomycin hydrochloride. Am J Hosp Pharm. 1971 Oct;28(10):760–763. [PubMed] [Google Scholar]
- Rubin J., Rogers W. A., Taylor H. M., Everett E. D., Prowant B. F., Fruto L. V., Nolph K. D. Peritonitis during continuous ambulatory peritoneal dialysis. Ann Intern Med. 1980 Jan;92(1):7–13. doi: 10.7326/0003-4819-92-1-7. [DOI] [PubMed] [Google Scholar]
- Wyatt R. G., Okamoto G. A., Feigin R. D. Stability of antibiotics in parenteral solutions. Pediatrics. 1972 Jan;49(1):22–29. [PubMed] [Google Scholar]