TABLE 1.

Expression of the TRAP-11β-HSD2 transgene does not alter basal bone geometry, mineral density, or vertebral cancellous histomorphometry in 6.5-month-old mice

Measurement	Wild-type (n = 8)	Transgenic (n = 7)
Geometry
Weight (g)	32.2 ± 4.3	35.1 ± 3.4
Vertebral height (mm)	3.4 ± 0.1	3.4 ± 0.1
Vertebral depth (mm)	1.3 ± 0.1	1.4 ± 0.1
Vertebral width (mm)	2.1 ± 0.4	2.3 ± 0.2
BMD (mg/mm2)	61.1 ± 3.1	62.4 ± 4.6
Histomorphometry
Bone area (%)	13.1 ± 3.3	13.4 ± 1.8
Trabecular width (μm)	35.2 ± 4.6	35.6 ± 2.8
Trabecular spacing (μm)	241.9 ± 41.2	233.5 ± 29.0
Trabecular number (/mm)	3.7 ± 0.5	3.8 ± 0.4
Wall width (μm)	7.3 ± 0.6	6.8 ± 1.2
Osteoid area (%)	1.6 ± 0.7	1.9 ± 0.8
Osteoid width (μm)	2.4 ± 0.2	2.5 ± 0.2
Osteoblast number (mm)	6.6 ± 1.9	7.2 ± 1.8
Osteoclast number (mm)	1.9 ± 0.3	1.7 ± 0.7

Values are given as mean ± SD of measurements.