Skip to main content
Antimicrobial Agents and Chemotherapy logoLink to Antimicrobial Agents and Chemotherapy
. 1982 Apr;21(4):681–682. doi: 10.1128/aac.21.4.681

Pharmacokinetics of potassium clavulanate in combination with amoxicillin in pediatric patients.

J D Nelson, H Kusmiesz, S Shelton
PMCID: PMC181969  PMID: 6979312

Abstract

Two dosages of a liquid suspension formulation of amoxicillin and potassium clavulanate were tested in 34 infants and children. The smaller dosage resulted in suboptimal plasma concentrations. With a greater dosage (3.3 mg of clavulanate per kg and 13.3 mg of amoxicillin per kg), the mean peak plasma concentrations were 1.6 micrograms clavulanic acid per ml and 4.9 micrograms amoxicillin per ml.

Full text

PDF

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Ginsburg C. M., McCracken G. H., Jr, Thomas M. L., Clahsen J. Comparative pharmacokinetics of amoxicillin and ampicillin in infants and children. Pediatrics. 1979 Nov;64(5):627–631. [PubMed] [Google Scholar]
  2. Hunter P. A., Coleman K., Fisher J., Taylor D. In vitro synergistic properties of clavulanic acid, with ampicillin, amoxycillin and ticarcillin. J Antimicrob Chemother. 1980 Jul;6(4):455–470. doi: 10.1093/jac/6.4.455. [DOI] [PubMed] [Google Scholar]

Articles from Antimicrobial Agents and Chemotherapy are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES