Abstract
Two litres of low molecular weight dextran in normal saline were given intravenously over 48 hours to 10 patients with systemic sclerosis and Raynaud's phenomenon. The finger temperatures of nine were recorded under standardized conditions. One patient had lowered temperatures of the fingers, two had a rise in temperature, and six had no change. There were no side effects of the treatment. None of the 10 patients showed any clinical improvement.
Full text
PDF
Images in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BIENENSTOCK J., HARDING E. L. LOW-MOLECULAR-WEIGHT DEXTRAN ('RHEOMACRODEX') IN ISCHAEMIC ULCERATION OF THE SKIN. Lancet. 1964 Mar 7;1(7332):524–525. doi: 10.1016/s0140-6736(64)92911-3. [DOI] [PubMed] [Google Scholar]
- BLAKEMORE W. S., FORSTER R. E., MORTON J. W., OGILVIE C. M. A standardized breath holding technique for the clinical measurement of the diffusing capacity of the lung for carbon monoxide. J Clin Invest. 1957 Jan;36(1 Pt 1):1–17. doi: 10.1172/JCI103402. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Evarts C. M. Low molecular weight dextran. Med Clin North Am. 1967 Sep;51(5):1285–1299. doi: 10.1016/s0025-7125(16)32995-9. [DOI] [PubMed] [Google Scholar]
- Holti G. The effect of intermittent low molecular dextran infusions upon the digital circulation in systemic sclerosis. Br J Dermatol. 1965 Nov;77(11):560–568. doi: 10.1111/j.1365-2133.1965.tb14576.x. [DOI] [PubMed] [Google Scholar]
- Morgan T. O., Little J. M., Evans W. A. Renal failure associated with low-molecular-weight dextran infusion. Br Med J. 1966 Sep 24;2(5516):737–739. doi: 10.1136/bmj.2.5516.737. [DOI] [PMC free article] [PubMed] [Google Scholar]
- POWLEY P. H. Rheomacrodex in peripheral ischemia. Lancet. 1963 Jun 1;1(7292):1189–1190. doi: 10.1016/s0140-6736(63)92483-8. [DOI] [PubMed] [Google Scholar]
- Singer A. Low-molecular-weight dextran in the treatment of peripheral arterial insufficiency. Lancet. 1965 Nov 20;2(7421):1050–1052. doi: 10.1016/s0140-6736(65)90574-x. [DOI] [PubMed] [Google Scholar]