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. 1992 Dec;58(12):3928–3931. doi: 10.1128/aem.58.12.3928-3931.1992

Production of the Mycotoxin Fumonisin B1 by Alternaria alternata f. sp. lycopersici

Junping Chen 1, Chester J Mirocha 1,*, Weiping Xie 1, Lawrence Hogge 1, Doug Olson 1
PMCID: PMC183206  PMID: 16348822

Abstract

The mycotoxin fumonisin B1, originally described as being produced by Fusarium moniliforme, was detected in liquid cultures of Alternaria alternata f. sp. lycopersici, a host-specific pathogen of tomato plants. The metabolite was detected by high-pressure liquid chromatography and mass spectrometry. Its identity was confirmed by fast atom bombardment and ion spray mass spectrometry, as well as parent-daughter tandem mass spectrometry. In three separate experiments, the concentrations found ranged between 5 and 140 ppm (μg/ml).

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Selected References

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  1. Bacon S. P. Effect of masker level on overshoot. J Acoust Soc Am. 1990 Aug;88(2):698–702. doi: 10.1121/1.399773. [DOI] [PubMed] [Google Scholar]
  2. Clouse S. D., Martensen A. N., Gilchrist D. G. Rapid purification of host-specific pathotoxins from Alternaria alternata f. sp. lycopersici by solid-phase adsorption on octadecylsilane. J Chromatogr. 1985 Dec 20;350(1):255–263. doi: 10.1016/s0021-9673(01)93524-1. [DOI] [PubMed] [Google Scholar]
  3. Engelhardt J. A., Carlton W. W., Tuite J. F. Toxicity of Fusarium moniliforme var. subglutinans for chicks, ducklings, and turkey poults. Avian Dis. 1989 Apr-Jun;33(2):357–360. [PubMed] [Google Scholar]
  4. Gelderblom W. C., Kriek N. P., Marasas W. F., Thiel P. G. Toxicity and carcinogenicity of the Fusarium moniliforme metabolite, fumonisin B1, in rats. Carcinogenesis. 1991 Jul;12(7):1247–1251. doi: 10.1093/carcin/12.7.1247. [DOI] [PubMed] [Google Scholar]
  5. Marasas W. F., Kellerman T. S., Gelderblom W. C., Coetzer J. A., Thiel P. G., van der Lugt J. J. Leukoencephalomalacia in a horse induced by fumonisin B1 isolated from Fusarium moniliforme. Onderstepoort J Vet Res. 1988 Dec;55(4):197–203. [PubMed] [Google Scholar]
  6. Mirocha C. J., Gilchrist D. G., Shier W. T., Abbas H. K., Wen Y., Vesonder R. F. AAL toxins, fumonisins (biology and chemistry) and host-specificity concepts. Mycopathologia. 1992 Feb;117(1-2):47–56. doi: 10.1007/BF00497278. [DOI] [PubMed] [Google Scholar]
  7. Ross P. F., Nelson P. E., Richard J. L., Osweiler G. D., Rice L. G., Plattner R. D., Wilson T. M. Production of fumonisins by Fusarium moniliforme and Fusarium proliferatum isolates associated with equine leukoencephalomalacia and a pulmonary edema syndrome in swine. Appl Environ Microbiol. 1990 Oct;56(10):3225–3226. doi: 10.1128/aem.56.10.3225-3226.1990. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Ross P. F., Rice L. G., Plattner R. D., Osweiler G. D., Wilson T. M., Owens D. L., Nelson H. A., Richard J. L. Concentrations of fumonisin B1 in feeds associated with animal health problems. Mycopathologia. 1991 Jun;114(3):129–135. doi: 10.1007/BF00437200. [DOI] [PubMed] [Google Scholar]

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