Abstract
beta-hydroxypropionaldehyde (3-HPA) can be oxidized to acrylic acid, an industrially important chemical used in the manufacture of synthetic plastics and other polymers. Of 19 genera and 55 strains tested, 3 Klebsiella and 2 Enterobacter strains produced 3-HPA. The most efficient strain was Klebsiella pneumoniae NRRL B-4011. Under optimum conditions (28 degrees C; 40 g of semicarbazide hydrochloride per liter, 70 g of glycerol per liter; and pH 6.0), 3.1 g of B-4011 cells per liter accumulated 22 g of 3-HPA per liter at a specific rate of 0.83 g/g per h; however, 14.5 g of cells per liter accumulated 46 g of 3-HPA per liter at a specific rate of 0.41 g/g per h.
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- ABELES R. H., BROWNSTEIN A. M., RANDLES C. H. beta-Hydroxypropionaldehyde, an intermediate in the formation of 1,3-propanediol by Aerobacter aerogenes. Biochim Biophys Acta. 1960 Jul 15;41:530–531. doi: 10.1016/0006-3002(60)90054-8. [DOI] [PubMed] [Google Scholar]
- Slininger P. J., Bothast R. J. Optimizing aerobic conversion of glycerol to 3-hydroxypropionaldehyde. Appl Environ Microbiol. 1985 Dec;50(6):1444–1450. doi: 10.1128/aem.50.6.1444-1450.1985. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Slininger P. J., Bothast R. J., Smiley K. L. Production of 3-hydroxypropionaldehyde from glycerol. Appl Environ Microbiol. 1983 Jul;46(1):62–67. doi: 10.1128/aem.46.1.62-67.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]