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. 1988 Aug 6;297(6645):391–395. doi: 10.1136/bmj.297.6645.391

Mortality in women in relation to their childbearing history.

A Green 1, V Beral 1, K Moser 1
PMCID: PMC1834270  PMID: 3408979

Abstract

With data from the Office of Population Censuses and Surveys' longitudinal study the mortality of currently married women aged under 60 in 1971 was investigated in relation to the number of liveborn children reported at the 1971 census, adjusting for their husbands' social class. Women who had never had children experienced a higher mortality from many causes of death than the parous women, and this was probably due, at least in part, to selective factors. When the analysis was confined to parous women mortality from diabetes mellitus and cervical cancer increased significantly and oesophageal cancer decreased significantly with increasing number of liveborn children. Mortality from all circulatory diseases and from hypertensive disease, ischaemic heart disease, and subarachnoid haemorrhage tended to rise with parity, though the trends were not statistically significant. Mortality from breast cancer decreased significantly with the number of liveborn children, but only when nullipara were included in the analyses. These data suggest that there may be residual and cumulative effects of childbearing which influence patterns of disease in the long term.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Beard C. M., Fuster V., Annegers J. F. Reproductive history in women with coronary heart disease. A case-control study. Am J Epidemiol. 1984 Jul;120(1):108–114. doi: 10.1093/oxfordjournals.aje.a113859. [DOI] [PubMed] [Google Scholar]
  2. Beral V. Long term effects of childbearing on health. J Epidemiol Community Health. 1985 Dec;39(4):343–346. doi: 10.1136/jech.39.4.343. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Beral V. Parity and susceptibility to cancer. Ciba Found Symp. 1983;96:182–203. doi: 10.1002/9780470720776.ch11. [DOI] [PubMed] [Google Scholar]
  4. Brinton L. A., Hamman R. F., Huggins G. R., Lehman H. F., Levine R. S., Mallin K., Fraumeni J. F., Jr Sexual and reproductive risk factors for invasive squamous cell cervical cancer. J Natl Cancer Inst. 1987 Jul;79(1):23–30. [PubMed] [Google Scholar]
  5. Byers T., Graham S., Swanson M. Parity and colorectal cancer risk in women. J Natl Cancer Inst. 1982 Nov;69(5):1059–1062. [PubMed] [Google Scholar]
  6. FITZGERALD M. G., MALINS J. M., O'SULLIVAN D. J., WALL M. The effect of sex and parity on the incidence of diabetes mellitus. Q J Med. 1961 Jan;30:57–70. [PubMed] [Google Scholar]
  7. Freinkel N. Banting Lecture 1980. Of pregnancy and progeny. Diabetes. 1980 Dec;29(12):1023–1035. doi: 10.2337/diab.29.12.1023. [DOI] [PubMed] [Google Scholar]
  8. Heliövaara M., Aromaa A. Parity and obesity. J Epidemiol Community Health. 1981 Sep;35(3):197–199. doi: 10.1136/jech.35.3.197. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Kvåle G., Heuch I., Eide G. E. A prospective study of reproductive factors and breast cancer. I. Parity. Am J Epidemiol. 1987 Nov;126(5):831–841. doi: 10.1093/oxfordjournals.aje.a114720. [DOI] [PubMed] [Google Scholar]
  10. Miller A. B., Barclay T. H., Choi N. W., Grace M. G., Wall C., Plante M., Howe G. R., Cinader B., Davis F. G. A study of cancer, parity and age at first pregnancy. J Chronic Dis. 1980;33(10):595–605. doi: 10.1016/0021-9681(80)90002-8. [DOI] [PubMed] [Google Scholar]
  11. OLIVER M. F., BOYD G. S. Plasma lipid and serum lipoprotein patterns during pregnancy and puerperium. Clin Sci. 1955 Feb;14(1):15–23. [PubMed] [Google Scholar]
  12. PYKE D. A. Parity and the incidence of diabetes. Lancet. 1956 Jun 2;270(6927):818–820. doi: 10.1016/s0140-6736(56)91293-4. [DOI] [PubMed] [Google Scholar]
  13. Potter J. D., McMichael A. J. Large bowel cancer in women in relation to reproductive and hormonal factors: a case-control study. J Natl Cancer Inst. 1983 Oct;71(4):703–709. [PubMed] [Google Scholar]
  14. Scott J. S. Sex hormones and gynaecological cancer. Br Med J (Clin Res Ed) 1982 Jun 5;284(6330):1657–1658. doi: 10.1136/bmj.284.6330.1657. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. WINKELSTEIN W., Jr, STENCHEVER M. A., LILIENFELD A. M. Occurrence of pregnancy, abortion, and artificial menopause among women with coronary artery disease: a preliminary study. J Chronic Dis. 1958 Apr;7(4):273–286. doi: 10.1016/0021-9681(58)90085-7. [DOI] [PubMed] [Google Scholar]

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