Abstract
The relations among parental reports of respiratory symptoms, bronchospasm measured after exercise, and the presence of visible fungal mould in the home was assessed in a population sample of 7 year old children (n = 873). Wheeze in the past year was the symptom most closely associated with reported dampness and particularly with mould. The unadjusted odds ratio relating mould and wheeze was 3.70 (95% confidence interval 2.22 to 6.15), and after adjustment for housing tenure, number of people per room, number of smokers in the household, and gas cooking this remained highly significant (odds ratio 3.00 (1.72 to 5.25)). The reduction in forced expiratory volume in one second after six minutes of free running was used to validate reporting of wheeze. At all levels of measured bronchial lability wheeze was reported more commonly in the children from homes with mould. There was no significant difference in the degree of bronchospasm measured among children from homes with and without mould. Awareness of dampness or mould in the home may be a determinant of parental reporting of symptoms and may account for much of the observed association between mould and respiratory symptoms.
Full text
PDF![1223](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f31/1834724/73ee1c9056b7/bmj00311-0017.png)
![1224](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f31/1834724/a911c6c08563/bmj00311-0018.png)
![1225](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f31/1834724/3faa7a1cd55e/bmj00311-0019.png)
![1226](https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f31/1834724/5164c95f3f83/bmj00311-0020.png)
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Anderson H. R., Bland J. M., Patel S., Peckham C. The natural history of asthma in childhood. J Epidemiol Community Health. 1986 Jun;40(2):121–129. doi: 10.1136/jech.40.2.121. [DOI] [PMC free article] [PubMed] [Google Scholar]
- BLOCK S. S. Humidity requirements for mold growth. Appl Microbiol. 1953 Nov;1(6):287–293. doi: 10.1128/am.1.6.287-293.1953. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Blythe M. E. Some aspects of the ecological study of the house dust mites. Br J Dis Chest. 1976 Jan;70(1):3–31. doi: 10.1016/0007-0971(76)90003-6. [DOI] [PubMed] [Google Scholar]
- Burr M. L., Dean B. V., Merrett T. G., Neale E., St Leger A. S., Verrier-Jones E. R. Effects of anti-mite measures on children with mite-sensitive asthma: a controlled trial. Thorax. 1980 Jul;35(7):506–512. doi: 10.1136/thx.35.7.506. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Burr M. L., St Leger A. S., Yarnell J. W. Wheezing, dampness, and coal fires. Community Med. 1981 Aug;3(3):205–209. doi: 10.1007/BF02549117. [DOI] [PubMed] [Google Scholar]
- Goldstein B. D., Melia R. J., Chinn S., Florey C. V., Clark D., John H. H. The relation between respiratory illness in primary schoolchildren and the use of gas for cooking--II. Factors affecting nitrogen dioxide levels in the home. Int J Epidemiol. 1979 Dec;8(4):339–345. doi: 10.1093/ije/8.4.339. [DOI] [PubMed] [Google Scholar]
- HILL A. B. THE ENVIRONMENT AND DISEASE: ASSOCIATION OR CAUSATION? Proc R Soc Med. 1965 May;58:295–300. doi: 10.1177/003591576505800503. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hetzel M. R., Millard F. J., Ayesh R., Bridges C. E., Nanson E. M., Swain C. P., Williams I. P. Laser treatment for carcinoma of the bronchus. Br Med J (Clin Res Ed) 1983 Jan 1;286(6358):12–16. doi: 10.1136/bmj.286.6358.12. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Holt P. G., Turner K. J. Environmental tobacco smoke. Effects in humans. Respiratory symptoms in the children of smokers: an overview. Eur J Respir Dis Suppl. 1984;133:109–120. [PubMed] [Google Scholar]
- Leaderer B. P. Air pollutant emissions from kerosene space heaters. Science. 1982 Dec 10;218(4577):1113–1115. doi: 10.1126/science.218.4577.1113. [DOI] [PubMed] [Google Scholar]
- Martin C. J., Platt S. D., Hunt S. M. Housing conditions and ill health. Br Med J (Clin Res Ed) 1987 May 2;294(6580):1125–1127. doi: 10.1136/bmj.294.6580.1125. [DOI] [PMC free article] [PubMed] [Google Scholar]
- McNichol K. N., Williams H. E. Spectrum of asthma in children. II. Allergic components. Br Med J. 1973 Oct 6;4(5883):12–16. doi: 10.1136/bmj.4.5883.12. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Melia R. J., Florey C. V., Chinn S. The relation between respiratory illness in primary schoolchildren and the use of gas for cooking--I. Results from a national survey. Int J Epidemiol. 1979 Dec;8(4):333–338. doi: 10.1093/ije/8.4.333. [DOI] [PubMed] [Google Scholar]
- Melia R. J., Florey C. du V., Morris R. W., Goldstein B. D., John H. H., Clark D., Craighead I. B., Mackinlay J. C. Childhood respiratory illness and the home environment. II. Association between respiratory illness and nitrogen dioxide, temperature and relative humidity. Int J Epidemiol. 1982 Jun;11(2):164–169. doi: 10.1093/ije/11.2.164. [DOI] [PubMed] [Google Scholar]
- Ogston S. A., Florey C. D., Walker C. H. The Tayside infant morbidity and mortality study: effect on health of using gas for cooking. Br Med J (Clin Res Ed) 1985 Mar 30;290(6473):957–960. doi: 10.1136/bmj.290.6473.957. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Platts-Mills T. A., Tovey E. R., Mitchell E. B., Moszoro H., Nock P., Wilkins S. R. Reduction of bronchial hyperreactivity during prolonged allergen avoidance. Lancet. 1982 Sep 25;2(8300):675–678. doi: 10.1016/s0140-6736(82)90709-7. [DOI] [PubMed] [Google Scholar]
- Proceedings of the British Thoracic Society. 1985 summer meeting. 3-5 July, York. Abstracts. Thorax. 1985 Sep;40(9):688–728. doi: 10.1136/thx.40.9.688. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Silverman M., Anderson S. D. Standardization of exercise tests in asthmatic children. Arch Dis Child. 1972 Dec;47(256):882–889. doi: 10.1136/adc.47.256.882. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Strachan D. P., Elton R. A. Relationship between respiratory morbidity in children and the home environment. Fam Pract. 1986 Sep;3(3):137–142. doi: 10.1093/fampra/3.3.137. [DOI] [PubMed] [Google Scholar]
- Ware J. H., Dockery D. W., Spiro A., 3rd, Speizer F. E., Ferris B. G., Jr Passive smoking, gas cooking, and respiratory health of children living in six cities. Am Rev Respir Dis. 1984 Mar;129(3):366–374. doi: 10.1164/arrd.1984.129.3.366. [DOI] [PubMed] [Google Scholar]
- Williams H., McNicol K. N. Prevalence, natural history, and relationship of wheezy bronchitis and asthma in children. An epidemiological study. Br Med J. 1969 Nov 8;4(5679):321–325. doi: 10.1136/bmj.4.5679.321. [DOI] [PMC free article] [PubMed] [Google Scholar]