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. 1982 Jul;22(1):51–54. doi: 10.1128/aac.22.1.51

In vitro activities of trimethoprim and sulfamethoxazole against Listeria monocytogenes.

D L Winslow, G A Pankey
PMCID: PMC183673  PMID: 6812496

Abstract

The in vitro activities of trimethoprim and sulfamethoxyazole against clinical isolates of Listeria monocytogenes were examined separately and in combination with a microtiter broth dilution system. Sulfamethoxazole demonstrated variable activity and was generally bacteriostatic. Trimethoprim alone was bactericidal against 96% of isolates at less than 0.5 microgram/ml. The bactericidal action of trimethoprim against L. monocytogenes was generally potentiated by sulfamethoxyazole even when isolates were relatively resistant to sulfamethoxyazole alone.

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Selected References

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