Abstract
The biliary excretion of six cephalosporins was examined in normal and partially hepatectomized rats. Cefamandole, cefazolin, cefuroxime, cefoxitin, and cephradine were excreted well in normal animals. In partially hepatectomized rats, the cumulative percentage of excretion reached only 11 to 36.8% of the control levels. Cephaloridine was excreted poorly in both groups.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Wright W. E., Line V. D. Biliary excretion of cephalosporins in rats: influence of molecular weight. Antimicrob Agents Chemother. 1980 May;17(5):842–846. doi: 10.1128/aac.17.5.842. [DOI] [PMC free article] [PubMed] [Google Scholar]