Abstract
Six cephalosporins and three aminoglycosides were examined for activity against 1,693 isolates belonging to six species of Proteeae. The most notable species-specific differences included the marked susceptibility of Providencia alcalifaciens and Proteus mirabilis to cephalothin, the resistance of Proteus vulgaris to cefamandole, and the resistance of Providencia stuartii to gentamicin and tobramycin. The third-generation cephalosporins cefotaxime and moxalactam were substantially more inhibitory than were cefoperazone, cefamandole, and cefoxitin. P. stuartii, generally the most resistant species, was, however, markedly susceptible to moxalactam and cefotaxime.
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Selected References
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- Adler J. L., Burke J. P., Martin D. F., Finland M. Proteus infections in a general hospital. II. Some clinical and epidemiological characteristis. With an analysis of 71 cases of proteus bacteremia. Ann Intern Med. 1971 Oct;75(4):531–536. doi: 10.7326/0003-4819-75-4-531. [DOI] [PubMed] [Google Scholar]
- Bhat P., Myers R. M., Feldman R. A. Providence group of organisms in the aetiology of juvenile diarrhoea. Indian J Med Res. 1971 Jul;59(7):1010–1018. [PubMed] [Google Scholar]
- Cosenza B. J., Podgwaite J. D. A new species of Proteus isolated from larvae of the gypsy moth Porthetria dispar (L.). Antonie Van Leeuwenhoek. 1966;32(2):187–191. doi: 10.1007/BF02097459. [DOI] [PubMed] [Google Scholar]
- Larsson P., Olling S. 0 antigen distribution and sensitivity to the bactericidal effect of normal human serum of Proteus strains from clinical specimens. Med Microbiol Immunol. 1977 Jul 18;163(2):77–82. doi: 10.1007/BF02121822. [DOI] [PubMed] [Google Scholar]
- Overturf G. D., Wilkins J., Ressler R. Emergence of resistance of Providencia stuartii to multiple antibiotics: speciation and biochemical characterization of Providencia. J Infect Dis. 1974 Mar;129(3):353–357. doi: 10.1093/infdis/129.3.353. [DOI] [PubMed] [Google Scholar]
- POTEE K. G., WRIGHT S. S., FINLAND M. In vitro susceptibility of recently isolated strains of Proteus to ten antibiotics. J Lab Clin Med. 1954 Sep;44(3):463–477. [PubMed] [Google Scholar]
- Penner J. L., Hinton N. A., Hamilton L. J., Hennessy J. N. Three episodes of nosocomial urinary tract infections caused by one O-serotype of Providencia stuartii. J Urol. 1981 May;125(5):668–671. doi: 10.1016/s0022-5347(17)55157-5. [DOI] [PubMed] [Google Scholar]
- Penner J. L., Hinton N. A., Hennessy J. Biotypes of Proteus rettgeri. J Clin Microbiol. 1975 Feb;1(2):136–142. doi: 10.1128/jcm.1.2.136-142.1975. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Penner J. L., Preston M. A. Differences among Providencia species in their in vitro susceptibilities to five antibiotics. Antimicrob Agents Chemother. 1980 Dec;18(6):868–871. doi: 10.1128/aac.18.6.868. [DOI] [PMC free article] [PubMed] [Google Scholar]
- STORY P. Proteus infections in hospital. J Pathol Bacteriol. 1954 Jul;68(1):55–62. doi: 10.1002/path.1700680107. [DOI] [PubMed] [Google Scholar]
- Washington J. A., 2nd, Senjem D. H., Haldorson A., Schutt A. H., Martin W. J. Nosocomially acquired bacteriuria due to Proteus rettgeri and Providencia stuartii. Am J Clin Pathol. 1973 Dec;60(6):836–838. doi: 10.1093/ajcp/60.6.836. [DOI] [PubMed] [Google Scholar]
- von Graevenitz A., Nourbakhsh M. Antimicrobial resistance of the genera Proteus, Providencia and Serratia with special reference to multiple resistance patterns. Med Microbiol Immunol. 1972;157(2):142–148. doi: 10.1007/BF02124474. [DOI] [PubMed] [Google Scholar]