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. 1982 Oct;22(4):693–695. doi: 10.1128/aac.22.4.693

Comparative Stability of Newly Introduced β-Lactam Antibiotics to Renal Dipeptidase

Hidetada Mikami 1, Mieko Ogashiwa 1, Yushi Saino 1, Matsuhisa Inoue 1, Susumu Mitsuhashi 1
PMCID: PMC183816  PMID: 7181478

Abstract

Renal dipeptidase purified from swine kidney hydrolyzed N-formimidoyl thienamycin, carpetimycins A and B, and Sch29482, but not azthreonam, penicillin G, or cephaloridine.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brown A. G., Corbett D. F., Eglington A. J., Howarth T. T. Structures of olivanic acid derivatives MM 22380, MM 22381, MM 22382 and MM 22383; four new antibiotics isolated from Streptomyces olivaceus. J Antibiot (Tokyo) 1979 Sep;32(9):961–963. doi: 10.7164/antibiotics.32.961. [DOI] [PubMed] [Google Scholar]
  2. Campbell B. J., Lin Y. C., Davis R. V., Ballew E. The purification and properties of a particulate renal dipeptidase. Biochim Biophys Acta. 1966 May 5;118(2):371–386. doi: 10.1016/s0926-6593(66)80046-2. [DOI] [PubMed] [Google Scholar]
  3. Hirai K., Iyobe S., Inoue M., Mitsuhashi S. Purification and properties of a new beta-lactamase from Pseudomonas cepacia. Antimicrob Agents Chemother. 1980 Mar;17(3):355–358. doi: 10.1128/aac.17.3.355. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Kahan J. S., Kahan F. M., Goegelman R., Currie S. A., Jackson M., Stapley E. O., Miller T. W., Miller A. K., Hendlin D., Mochales S. Thienamycin, a new beta-lactam antibiotic. I. Discovery, taxonomy, isolation and physical properties. J Antibiot (Tokyo) 1979 Jan;32(1):1–12. doi: 10.7164/antibiotics.32.1. [DOI] [PubMed] [Google Scholar]
  5. Kimura Y., Motokawa K., Nagata H., Kameda Y., Matsuura S., Mayama M., Yoshida T. Asparenomycins A, B and C, new carbapenem antibiotics. IV. Antibacterial activity. J Antibiot (Tokyo) 1982 Jan;35(1):32–38. doi: 10.7164/antibiotics.35.32. [DOI] [PubMed] [Google Scholar]
  6. Kropp H., Sundelof J. G., Kahan J. S., Kahan F. M., Birnbaum J. MK0787 (N-formimidoyl thienamycin): evaluation of in vitro and in vivo activities. Antimicrob Agents Chemother. 1980 Jun;17(6):993–1000. doi: 10.1128/aac.17.6.993. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. LOWRY O. H., ROSEBROUGH N. J., FARR A. L., RANDALL R. J. Protein measurement with the Folin phenol reagent. J Biol Chem. 1951 Nov;193(1):265–275. [PubMed] [Google Scholar]
  8. Nakayama M., Iwasaki A., Kimura S., Mizoguchi T., Tanabe S., Murakami A., Watanabe I., Okuchi M., Itoh H., Saino Y. Carpetimycins A and B, new beta-lactam antibiotics. J Antibiot (Tokyo) 1980 Nov;33(11):1388–1390. doi: 10.7164/antibiotics.33.1388. [DOI] [PubMed] [Google Scholar]
  9. Sakamoto M., Iguchi H., Okamura K., Hori S., Fukagawa Y., Ishikura T., Lein J. PS-5, a new beta-lactam antibiotic. II. Antimicrobial activity. J Antibiot (Tokyo) 1979 Apr;32(4):272–279. doi: 10.7164/antibiotics.32.272. [DOI] [PubMed] [Google Scholar]
  10. Stapley E. O., Cassidy P. J., Tunac J., Monaghan R. L., Jackson M., Hernandez S., Zimmerman S. B., Mata J. M., Currie S. A., Daoust D. Epithienamycins-novel beta-lactams related to thienamycin. I. Production and antibacterial activity. J Antibiot (Tokyo) 1981 Jun;34(6):628–636. doi: 10.7164/antibiotics.34.628. [DOI] [PubMed] [Google Scholar]
  11. Sugiura M., Ito Y., Hirano K., Sawaki S. Purification and properties of human kidney dipeptidases. Biochim Biophys Acta. 1978 Feb 10;522(2):541–550. doi: 10.1016/0005-2744(78)90086-4. [DOI] [PubMed] [Google Scholar]
  12. Sykes R. B., Bonner D. P., Bush K., Georgopapadakou N. H. Azthreonam (SQ 26,776), a synthetic monobactam specifically active against aerobic gram-negative bacteria. Antimicrob Agents Chemother. 1982 Jan;21(1):85–92. doi: 10.1128/aac.21.1.85. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Toda M., Sato K., Nakazawa H., Inoue M., Mitsuhashi S. Effect of N-formimidoyl thienamycin (MK0787) on beta-lactamases and activity against beta-lactamase-producing strains. Antimicrob Agents Chemother. 1980 Nov;18(5):837–838. doi: 10.1128/aac.18.5.837. [DOI] [PMC free article] [PubMed] [Google Scholar]

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