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Ets1 regulates IL-8 expression and secretion in SK-N-SH cells. (A) Cells were transfected with the Ets1 expression plasmid, and then Western blot analysis was performed. (B) IL-8 promoter transcriptional activity was enhanced by cotransfection with Ets1 expression plasmid (mean ± SEM; *P < .05 vs control vector). (C) IL-8 secretion into a culture supernatant was increased by Ets1 overexpression (mean ± SEM; *P < .05 vs control vector).
