Abstract
In studies at 5 degrees C and pH 9.0, poliovirus 1 was inactivated about 15 times more rapidly by free chlorine (FC) in purified water in the presence of 1,262 mg of KCl per liter (approximately 0.0169 M) than in the absence of KCl. In the presence of 526 mg of KCl per liter, the virus was inactivated about seven times more rapidly by FC than in the absence of KCl. At a level of 21 mg/liter, KCl did not significantly potentiate the virucidal activity of FC in purified water. Although poliovirus 1 was inactivated almost three times more rapidly by FC in borate-buffered purified water than in purified water, the presence of the buffer did not alter the extent of potentiation by KCl. Most of FC exists as OCl- at pH 9.0. Tap water has been shown to markedly potentiate the polivirucidal effectiveness of FC at pH 9.0. For the same degree of virucidal potentiation of FC at this pH, a considerably greater quantity of KCl was required in purified water than the total salt content that appeared to be present in the tap water.
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Selected References
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- Berg G., Sanjaghsaz H., Wangwongwatana S. Potentiation of the poliocidal effectiveness of free chlorine by a buffer. J Virol Methods. 1989 Feb;23(2):179–186. doi: 10.1016/0166-0934(89)90131-6. [DOI] [PubMed] [Google Scholar]
- Berg G., Sanjaghsaz H., Wangwongwatana S. Potentiation of the virucidal effectiveness of free chlorine by substances in drinking water. Appl Environ Microbiol. 1989 Feb;55(2):390–393. doi: 10.1128/aem.55.2.390-393.1989. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Cantor K. P., Hoover R., Hartge P., Mason T. J., Silverman D. T., Altman R., Austin D. F., Child M. A., Key C. R., Marrett L. D. Bladder cancer, drinking water source, and tap water consumption: a case-control study. J Natl Cancer Inst. 1987 Dec;79(6):1269–1279. [PubMed] [Google Scholar]
- DULBECCO R., VOGT M. Plaque formation and isolation of pure lines with poliomyelitis viruses. J Exp Med. 1954 Feb;99(2):167–182. doi: 10.1084/jem.99.2.167. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Dahling D. R., Berg G., Berman D. BGM, a continuous cell line more sensitive than primary rhesus and African green kidney cells for the recovery of viruses from water. Health Lab Sci. 1974 Oct;11(4):275–282. [PubMed] [Google Scholar]
- Engelbrecht R. S., Weber M. J., Salter B. L., Schmidt C. A. Comparative inactivation of viruses by chlorine. Appl Environ Microbiol. 1980 Aug;40(2):249–256. doi: 10.1128/aem.40.2.249-256.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Jensen H., Thomas K., Sharp D. G. Inactivation of coxsackieviruses B3 and B5 in water by chlorine. Appl Environ Microbiol. 1980 Sep;40(3):633–640. doi: 10.1128/aem.40.3.633-640.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sharp D. G., Leong J. Inactivation of poliovirus I (Brunhilde) single particles by chlorine in water. Appl Environ Microbiol. 1980 Aug;40(2):381–385. doi: 10.1128/aem.40.2.381-385.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sharp D. G., Young D. C., Floyd R., Johnson J. D. Effect of ionic environment on the inactivation of poliovirus in water by chlorine. Appl Environ Microbiol. 1980 Mar;39(3):530–534. doi: 10.1128/aem.39.3.530-534.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]