Abstract
Carbenicillin, piperacillin, and mezlocillin, when combined with cefoxitin, exhibited synergism against 20, 13, and 10 isolates of Bacteroides fragilis, respectively, and no antagonism was observed in 19 of 20 strains. These results suggest that if beta-lactamase was induced from B. fragilis by cefoxitin, it was ineffective against the antibiotics tested.
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Selected References
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- Grimm H. Bacteriological antagonism between acylureidopenicillins and cephalosporins. J Antimicrob Chemother. 1982 Jan;9 (Suppl A):31–34. doi: 10.1093/jac/9.suppl_a.31. [DOI] [PubMed] [Google Scholar]
- Kuck N. A., Testa R. T., Forbes M. In vitro and in vivo antibacterial effects of combinations of beta-lactam antibiotics. Antimicrob Agents Chemother. 1981 Apr;19(4):634–638. doi: 10.1128/aac.19.4.634. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Neu H. C., Labthavikul P. Combination of mezlocillin and azlocillin with cephalosporin antibiotics: cefoxitin, cefoperazone, cefotaxime and moxalactam. J Antimicrob Chemother. 1982 Jan;9 (Suppl A):101–106. doi: 10.1093/jac/9.suppl_a.101. [DOI] [PubMed] [Google Scholar]
- SABATH L. D., ABRAHAM E. P. SYNERGISTIC ACTION OF PENICILLINS AND CEPHALOSPORINS AGAINST PSEUDOMONAS PYOCYANEA. Nature. 1964 Dec 12;204:1066–1069. doi: 10.1038/2041066a0. [DOI] [PubMed] [Google Scholar]
- Sanders C. C., Sanders W. E., Jr, Goering R. V. In vitro antagonism of beta-lactam antibiotics by cefoxitin. Antimicrob Agents Chemother. 1982 Jun;21(6):968–975. doi: 10.1128/aac.21.6.968. [DOI] [PMC free article] [PubMed] [Google Scholar]
