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. 1983 Jan;23(1):185–187. doi: 10.1128/aac.23.1.185

Effect of ketoconazole on the fungicidal action of amphotericin B in Candida albicans.

I J Sud, D S Feingold
PMCID: PMC184642  PMID: 6299182

Abstract

Amphotericin B-susceptible Candida albicans became resistant to the drug after growth in the presence of ketoconazole. Chromatographic analysis of cellular sterols showed that the organisms became depleted of ergosterol in parallel with the development of amphotericin B resistance. The implications of these findings are discussed in relation to combination chemotherapy with these two important antifungal agents.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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