Abstract
Resistance to clindamycin, erythromycin, and streptogramins in Clostridium difficile could be transferred to a susceptible strain by mixed culture at low frequencies (1 × 10−8 to 4 − 10−8 per donor cell). Transfer of tetracycline resistance occurred at frequencies of 3 × 10−7 to 5 × 10−7. No plasmid DNA involved in these transfers could be detected.
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