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. 1983 Jun;23(6):926–929. doi: 10.1128/aac.23.6.926

Polyoxin D inhibits growth of zoopathogenic fungi.

J M Becker, N L Covert, P Shenbagamurthi, A S Steinfeld, F Naider
PMCID: PMC185006  PMID: 6351734

Abstract

We demonstrated that polyoxin D at millimolar concentrations caused marked morphological alterations of the human pathogens Candida albicans and Cryptococcus neoformans. C. albicans incubated in the presence of this drug grew in long chains that were severely swollen. Polyoxin D inhibited the growth of C. neoformans and killed cells of both the yeast and the hyphal phase of C. albicans. These observations give the first evidence that polyoxin antibiotics can kill zoopathogenic fungi.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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