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. 1983 Jun;23(6):935–937. doi: 10.1128/aac.23.6.935

In vitro susceptibility of Mycobacterium fortuitum to amoxicillin or cephalothin in combination with clavulanic acid.

M H Cynamon, G S Palmer
PMCID: PMC185011  PMID: 6604496

Abstract

The comparative in vitro activity of cefoxitin, cephalothin, amoxicillin, and clavulanic acid in combination with the latter two agents against 13 isolates of Mycobacterium fortuitum was evaluated by agar dilution susceptibility testing. Amoxicillin was more active than cephalothin but less active than cefoxitin against the strains tested. Clavulanic acid in combination with these beta-lactams usually improved the activity by one or two dilutions compared with the beta-lactams alone.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Bradford M. M. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem. 1976 May 7;72:248–254. doi: 10.1006/abio.1976.9999. [DOI] [PubMed] [Google Scholar]
  2. Cynamon M. H., Palmer G. S. In vitro susceptibility of Mycobacterium fortuitum to N-formimidoyl thienamycin and several cephamycins. Antimicrob Agents Chemother. 1982 Dec;22(6):1079–1081. doi: 10.1128/aac.22.6.1079. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Cynamon M. H., Patapow A. In vitro susceptibility of Mycobacterium fortuitum to cefoxitin. Antimicrob Agents Chemother. 1981 Jan;19(1):205–207. doi: 10.1128/aac.19.1.205. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Kasik J. E., Peacham L. Properties of beta-lactamases produced by three species of mycobacteria. Biochem J. 1968 May;107(5):675–682. doi: 10.1042/bj1070675. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. O'Callaghan C. H. Description and classification of the newer cephalosporins and their relationships with the established compounds. J Antimicrob Chemother. 1979 Nov;5(6):635–671. doi: 10.1093/jac/5.6.635. [DOI] [PubMed] [Google Scholar]
  6. O'Callaghan C. H., Morris A., Kirby S. M., Shingler A. H. Novel method for detection of beta-lactamases by using a chromogenic cephalosporin substrate. Antimicrob Agents Chemother. 1972 Apr;1(4):283–288. doi: 10.1128/aac.1.4.283. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Verbist L. In vitro activity of temocillin (BRL 17421), a novel beta-lactamase-stable penicillin. Antimicrob Agents Chemother. 1982 Jul;22(1):157–161. doi: 10.1128/aac.22.1.157. [DOI] [PMC free article] [PubMed] [Google Scholar]

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