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. 1983 Jun;23(6):941–943. doi: 10.1128/aac.23.6.941

Cefmenoxime penetration into gallbladder bile and tissue.

B R Smith, J LeFrock, B B Carr
PMCID: PMC185014  PMID: 6311092

Abstract

Cefmenoxime concentrations in gallbladder bile and tissue were assessed in patients undergoing cholecystectomy. A 0.5-g intravenous dose produced mean concentrations in bile of 54.1 micrograms/ml at 62.9 min and 56.3 micrograms/ml at 194 min after the dose was given. A 1.0-g intravenous dose produced concentrations in bile of 117.9 micrograms/ml at 53 min and 169.7 micrograms/ml of 194 min after the dose was given. Mean concentrations in tissue ranged from 6.1 to 17.9 micrograms/g. Biliary tree penetration was dose and time dependent. Therapeutic concentrations were achieved.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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