Table 3.
Metabolite* | Tissue | AD | Control | AD-control† |
---|---|---|---|---|
[NAA] | WML | 1.01 ± 0.54 | 0.99 ± 0.43 | +2 |
WM | 1.16 ± 0.22 | 1.19 ± 0.24 | −3 | |
[Cho] | WML | 0.55 ± 0.32 | 0.51 ± 0.38 | +8 |
WM | 0.42 ± 0.11 | 0.44 ± 0.07 | −4 | |
[Cr] | WML | 0.48 ± 0.19 | 0.45 ± 0.29 | +7 |
WM | 0.45 ± 0.10 | 0.47 ± 0.09 | −4 |
Concentration in arbitrary units.
Percent change in 41 patients with AD compared with 40 cognitively normal subjects.
WML = white matter lesion; WM = white matter (normal).