Skip to main content
Antimicrobial Agents and Chemotherapy logoLink to Antimicrobial Agents and Chemotherapy
. 1984 Jan;25(1):142–144. doi: 10.1128/aac.25.1.142

Effect of temocillin in combination with other beta-lactam antibiotics.

L Verbist, J Verhaegen
PMCID: PMC185455  PMID: 6703679

Abstract

The antibacterial interactions of temocillin with other beta-lactams were tested by checkerboard combination in Mueller-Hinton agar against 146 strains of members of the family Enterobacteriaceae, 35 Pseudomonas aeruginosa strains, and 35 Staphylococcus aureus strains. Most combinations showed a moderate degree of synergism. In only one Klebsiella strain was minor antagonism observed between temocillin and ampicillin.

Full text

PDF
142

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Fu K. P., Neu H. C. Synergistic activity of cefoperazone in combination with beta-lactamase inhibitors. J Antimicrob Chemother. 1981 Mar;7(3):287–292. doi: 10.1093/jac/7.3.287. [DOI] [PubMed] [Google Scholar]
  2. Jules K., Neu H. C. Antibacterial activity and beta-lactamase stability of temocillin. Antimicrob Agents Chemother. 1982 Sep;22(3):453–460. doi: 10.1128/aac.22.3.453. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Moellering R. C., Jr, Willey S., Eliopoulos G. M. Synergism and antagonism of ceftizoxime and other new cephalosporins. J Antimicrob Chemother. 1982 Nov;10 (Suppl 100):69–79. doi: 10.1093/jac/10.suppl_c.69. [DOI] [PubMed] [Google Scholar]
  4. Neu H. C. Combination of ceftizoxime with azlocillin, mezlocillin, piperacillin and ticarcillin. J Antimicrob Chemother. 1982 Nov;10 (Suppl 100):63–68. doi: 10.1093/jac/10.suppl_c.63. [DOI] [PubMed] [Google Scholar]
  5. Neu H. C., Labthavikul P. Combination of mezlocillin and azlocillin with cephalosporin antibiotics: cefoxitin, cefoperazone, cefotaxime and moxalactam. J Antimicrob Chemother. 1982 Jan;9 (Suppl A):101–106. doi: 10.1093/jac/9.suppl_a.101. [DOI] [PubMed] [Google Scholar]
  6. Slocombe B., Basker M. J., Bentley P. H., Clayton J. P., Cole M., Comber K. R., Dixon R. A., Edmondson R. A., Jackson D., Merrikin D. J. BRL 17421, a novel beta-lactam antibiotic, highly resistant to beta-lactamases, giving high and prolonged serum levels in humans. Antimicrob Agents Chemother. 1981 Jul;20(1):38–46. doi: 10.1128/aac.20.1.38. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Verbist L. In vitro activity of temocillin (BRL 17421), a novel beta-lactamase-stable penicillin. Antimicrob Agents Chemother. 1982 Jul;22(1):157–161. doi: 10.1128/aac.22.1.157. [DOI] [PMC free article] [PubMed] [Google Scholar]

Articles from Antimicrobial Agents and Chemotherapy are provided here courtesy of American Society for Microbiology (ASM)

RESOURCES