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. 1984 Feb;25(2):268–272. doi: 10.1128/aac.25.2.268

Detection of PSE-2 beta-lactamase in enterobacteria.

D M Livermore, J P Maskell, J D Williams
PMCID: PMC185487  PMID: 6608920

Abstract

PSE-2, a plasmid-mediated beta-lactamase which was previously considered pseudomonas specific, was observed in clinical isolates of Escherichia coli, Klebsiella pneumoniae, Providencia stuartii, and Enterobacter cloacae. All four isolates transferred PSE-2 production, together with resistance to gentamicin, tobramycin, kanamycin, and sulfamethoxazole, into Escherichia coli J62-1 and Pseudomonas aeruginosa PU21. Transfer correlated with acquisition by the transconjugants of a 65-megadalton plasmid, and this element was considered to encode PSE-2 expression. The PSE-2 enzyme conferred high-level carbenicillin resistance on both J62-1 and PU21 transconjugants, although the PSE-2-producing Providencia stuartii isolate was susceptible to carbenicillin.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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