Abstract
Chelation of copper by siderophores enhanced the toxicity of copper for Bacillus megaterium. Although this antibacterial activity appeared to be rapidly bactericidal, it could be partly reversed by addition of deferrisiderophore , or of ferrisiderophore at high concentration, immediately after exposure of cells to the cupric-siderophore complex.
Full text
PDFImages in this article
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Arceneaux J. E., Byers B. R. Ferric hydroxamate transport without subsequent iron utilization in Bacillus megaterium. J Bacteriol. 1976 Sep;127(3):1324–1330. doi: 10.1128/jb.127.3.1324-1330.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Arceneaux J. E., Byers B. R. Ferrisiderophore reductase activity in Bacillus megaterium. J Bacteriol. 1980 Feb;141(2):715–721. doi: 10.1128/jb.141.2.715-721.1980. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ecker D. J., Passavant C. W., Emery T. Role of two siderophores in Ustilago sphaerogena. Regulation of biosynthesis and uptake mechanisms. Biochim Biophys Acta. 1982 Jun 8;720(3):242–249. doi: 10.1016/0167-4889(82)90047-7. [DOI] [PubMed] [Google Scholar]
- Emery T., Hoffer P. B. Siderophore-mediated mechanism of gallium uptake demonstrated in the microorganism Ustilago sphaerogena. J Nucl Med. 1980 Oct;21(10):935–939. [PubMed] [Google Scholar]
- Leong J., Neilands J. B. Mechanisms of siderophore iron transport in enteric bacteria. J Bacteriol. 1976 May;126(2):823–830. doi: 10.1128/jb.126.2.823-830.1976. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rogers H. J., Synge C., Woods V. E. Antibacterial effect of scandium and indium complexes of enterochelin on Klebsiella pneumoniae. Antimicrob Agents Chemother. 1980 Jul;18(1):63–68. doi: 10.1128/aac.18.1.63. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Rogers H. J., Woods V. E., Synge C. Antibacterial effect of the scandium and indium complexes of enterochelin on Escherichia coli. J Gen Microbiol. 1982 Oct;128(10):2389–2394. doi: 10.1099/00221287-128-10-2389. [DOI] [PubMed] [Google Scholar]
- Weinberg E. D. Iron and infection. Microbiol Rev. 1978 Mar;42(1):45–66. doi: 10.1128/mr.42.1.45-66.1978. [DOI] [PMC free article] [PubMed] [Google Scholar]