Table 5 Diagnostic accuracy of the AST platelet ratio index (APRI) and Bonacini model in predicting cirrhosis in the study group.
| Cut off point | Fibrosis stage | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | ||
|---|---|---|---|---|---|---|---|
| All patients (n = 263) (n (%)) | Stage 0–3 (n = 223) (n (%)) | Stage 4 (n = 40) (n (%)) | |||||
| APRI | |||||||
| <1 | 135 (51) | 126 (57) | 9 (22) | 78 | 57 | 24 | 93 |
| >1 | 128 (49) | 97 (43) | 31 (78) | ||||
| <2 | 217 (83) | 198 (89) | 19 (47) | ||||
| >2 | 46 (17) | 25 (11) | 21 (53) | 53 | 89 | 46 | 91 |
| Bonacini model10 | |||||||
| <3 | 21 (8) | 21 (9) | 0 (0) | 100 | 9 | 17 | 100 |
| >3 | 242 (92) | 202 (91) | 40 (100) | ||||
| <7 | 208 (79) | 185 (83) | 23 (57) | ||||
| >7 | 55 (21) | 38 (17) | 17 (43) | 43 | 83 | 31 | 89 |
PPV, positive predictive value; NPV, negative predictive value.