Table 3 Functional group analysis based on cellular or biological gene ontology terms (GO‐term)12.
Observed | Expected | Enrichment ratio | p Value | p‐fdr | p‐bonf | |
---|---|---|---|---|---|---|
Cellular GO‐term | ||||||
Cytosolic ribosome (sensu Eukaryota) | 15 | 2.15 | 6.98 | <0.00001 | 0.00135 | 0.00674 |
Intracellular non‐membrane bound organelle | 113 | 56.23 | 2.01 | <0.00001 | 0.00135 | 0.00674 |
Ribosome | 33 | 8.22 | 4.01 | <0.00001 | 0.00135 | 0.00674 |
Vacuole | 20 | 5.55 | 3.6 | <0.00001 | 0.00135 | 0.00674 |
Large ribosomal subunit | 11 | 2.04 | 5.39 | <0.00001 | 0.00135 | 0.00674 |
Chromosome | 28 | 11.22 | 2.5 | 0.00001 | 0.00225 | 0.01348 |
Chromosome, pericentric region | 9 | 1.7 | 5.29 | 0.00003 | 0.00578 | 0.04044 |
Spindle | 11 | 2.72 | 4.04 | 0.00006 | 0.01011 | 0.08088 |
Nucleolus | 12 | 4.08 | 2.94 | 0.00066 | 0.09885 | 0.88968 |
Biological GO‐term | ||||||
Cell proliferation | 105 | 55.28 | 1.9 | <0.00001 | 0.00733 | 0.01466 |
DNA metabolism | 57 | 26.68 | 2.14 | <0.00001 | 0.00733 | 0.01466 |
Nucleotide metabolism | 23 | 9.48 | 2.43 | 0.00007 | 0.05131 | 0.20524 |
Macromolecule biosynthesis | 63 | 38.75 | 1.63 | 0.00007 | 0.05131 | 0.20524 |
Nucleotide biosynthesis | 18 | 6.77 | 2.66 | 0.00013 | 0.07623 | 0.38116 |
Significance value (p) is corrected for multiple testing by the method of Benjamini‐Hochberg (p‐fdr) and the method of Bonferroni (p‐bonf). Only significantly enriched gene ontology terms with p‐fdr <0.1 are shown.