Table 2 Variables of the internal cohort used to build the neural network.
Variable | Internal cohort (Bologna) | External cohort (London) | ||||
---|---|---|---|---|---|---|
Survivors (n = 213) | Dead (n = 38) | p Value | Survivors (n = 120) | Dead (n = 17) | p Value | |
AST (IU/l) | 93.7 (68.6) | 116.6 (105.8) | 0.207 | 84.2 (65.6) | 116.1 (101.9) | 0.253 |
Total bilirubin (mg/dl) | 3.4 (2.9) | 11.7 (9.6) | 0.001 | 4.1 (5.4) | 9.0 (8.5) | 0.015 |
GGT (IU/l) | 77.3 (63.9) | 43.1 (25.4) | 0.001 | 186.7 (43.3) | 81.0 (79.5) | 0.007 |
ALP (IU/l) | 357.1 (219.0) | 302.9 (110.1) | 0.137 | 281.1 (152.5) | 224.7 (204.9) | 0.469 |
Creatinine (mg/dl) | 0.92 (0.21) | 1.02 (0.29) | 0.011 | 1.28 (1.23) | 1.79 (1.64) | 0.044 |
Albumin (g/dl) | 3.1 (0.4) | 2.9 (0.4) | 0.016 | 3.1 (0.6) | 2.5 (0.8) | 0.001 |
INR | 1.57 (0.31) | 2.11 (0.54) | 0.001 | 1.21 (0.37) | 1.68 (0.83) | 0.017 |
Platelet count (×103/mm3) | 74.7 (53.8) | 64.6 (37.8) | 0.267 | 149.1 (135.3) | 112.7 (103.5) | 0.294 |
WBC (×103/mm3) | 4.3 (1.6) | 5.5 (2.2) | 0.002 | 6.1 (5.1) | 7.5 (6.3) | 0.236 |
Haemoglobin (g/dl) | 12.1 (5.7) | 10.2 (1.3) | 0.038 | 11.1 (1.9) | 10.6 (2.4) | 0.229 |
ALP, alkaline phosphatase; AST, aspartate aminotransferase; GGT, γ‐glutamyl‐transpeptidase; INR, international normalised ratio; WBC, white cell.
Continuous variables are reported as mean (SD).