Abstract
Plasmids R26 (Inc P) and R55-1 (Inc C) specify inducible nonenzymatic resistance to chloramphenicol. Escherichia coli K-12 strains harboring these plasmids encoded low-level resistance to thiamphenicol analogs Sch 25298 and Sch 25393 but failed to specify resistance to the fluorinated chloramphenicol analog Sch 24893. The analogs were efficient inducers of high-level chloramphenicol resistance.
Full text
PDF
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Chabbert Y. A., Scavizzi M. R., Witchitz J. L., Gerbaud G. R., Bouanchaud D. H. Incompatibility groups and the classification of fi - resistance factors. J Bacteriol. 1972 Nov;112(2):666–675. doi: 10.1128/jb.112.2.666-675.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Foster T. J., Walsh A. Phenotypic characterization of R-factor tetracycline resistance determinants. Genet Res. 1974 Dec;24(3):333–343. doi: 10.1017/s0016672300015330. [DOI] [PubMed] [Google Scholar]
- Gaffney D. F., Cundliffe E., Foster T. J. Chloramphenicol resistance that does not involve chloramphenicol acetyltransferase encoded by plasmids from gram-negative bacteria. J Gen Microbiol. 1981 Jul;125(1):113–121. doi: 10.1099/00221287-125-1-113. [DOI] [PubMed] [Google Scholar]
- Kono M., O'Hara K. Mechanism of chloramphenicol-resistance mediated by kR102 factor in Pseudomonas aeruginosa. J Antibiot (Tokyo) 1976 Feb;29(2):176–180. doi: 10.7164/antibiotics.29.176. [DOI] [PubMed] [Google Scholar]
- Nagai Y., Mitsuhashi S. New type of R factors incapable of inactivating chloramphenicol. J Bacteriol. 1972 Jan;109(1):1–7. doi: 10.1128/jb.109.1.1-7.1972. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Shaw W. V. The enzymatic acetylation of chloramphenicol by extracts of R factor-resistant Escherichia coli. J Biol Chem. 1967 Feb 25;242(4):687–693. [PubMed] [Google Scholar]
- Stanisich V. A., Bennett P. M., Oritz J. M. A molecular analysis of transductional marker rescue involving P-group plasmids in Pseudomonas aeruginosa. Mol Gen Genet. 1976 Feb 2;143(3):333–337. doi: 10.1007/BF00269412. [DOI] [PubMed] [Google Scholar]
- Suzuki Y., Okamoto S. The enzymatic acetylation of chloramphenicol by the multiple drug-resistant Escherichia coli carrying R factor. J Biol Chem. 1967 Oct 25;242(20):4722–4730. [PubMed] [Google Scholar]