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. 1983 Sep;17(3):180–183. doi: 10.1136/bjsm.17.3.180

Immediate effects of heavy exercise on the circulating thyroid hormones.

A R Siddiqui, R B Hinnefeld, T Dillon, W E Judson
PMCID: PMC1859160  PMID: 6652401

Abstract

Sera from 20 patients with suspected or known coronary artery disease were measured for thyroxine (T4), tri-iodothyronine (T3), tri-iodothyronine uptake ratio (T3UR), thyroid stimulating hormone (TSH), and reverse tri-iodothyronine (rT3), before and after maximal or near-maximal exercise. On the average the patients achieved 92% (rang 68-108) of the predicted maximum heart rate. There were no statistically significant differences between the pre- and the post-exercise serum levels of thyroid hormones. When five patients who achieved less than 90% of the predicted maximum heart rate were excluded, the results remained unchanged. It appears that the circulating thyroid hormones are not acutely affected after maximal or near-maximal exercise; however, the patient population was highly select.

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Selected References

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  1. Ahlborg G., Felig P., Hagenfeldt L., Hendler R., Wahren J. Substrate turnover during prolonged exercise in man. Splanchnic and leg metabolism of glucose, free fatty acids, and amino acids. J Clin Invest. 1974 Apr;53(4):1080–1090. doi: 10.1172/JCI107645. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Balsam A., Leppo L. E. Effect of physical training on the metabolism of thyroid hormones in man. J Appl Physiol. 1975 Feb;38(2):212–215. doi: 10.1152/jappl.1975.38.2.212. [DOI] [PubMed] [Google Scholar]
  3. Bayer M. F., McDougall I. R. Radioimmunoassay of free thyroxine in serum: comparison with clinical findings and results of conventional thyroid-function tests. Clin Chem. 1980 Jul;26(8):1186–1192. [PubMed] [Google Scholar]
  4. Berchtold P., Berger M., Cüppers H. J., Herrmann J., Nieschlag E., Rudorff K., Zimmermann H., Krüskemper H. L. Non-glucoregulatory hormones (T4, T3, rT3, TSH, testosterone) during physical exercise in juvenile type diabetics. Horm Metab Res. 1978 Jul;10(4):269–273. doi: 10.1055/s-0028-1093412. [DOI] [PubMed] [Google Scholar]
  5. CLARK F., HORN D. B. ASSESSMENT OF THYROID FUNCTION BY THE COMBINED USE OF THE SERUM PROTEIN-BOUND IODINE AND RESIN UPTAKE OF 131-I-TRIIODOTHYRONINE. J Clin Endocrinol Metab. 1965 Jan;25:39–45. doi: 10.1210/jcem-25-1-39. [DOI] [PubMed] [Google Scholar]
  6. Caralis D. G., Edwards L., Davis P. J. Serum total and free thyroxine and triiodothyronine during dynamic muscular exercise in man. Am J Physiol. 1977 Aug;233(2):E115–E118. doi: 10.1152/ajpendo.1977.233.2.E115. [DOI] [PubMed] [Google Scholar]
  7. De Nayer P., Malvaux P., Ostyn M., Van den Schrieck H. G., Beckers C., De Visscher M. Serum free thyroxine and binding-proteins after muscular exercise. J Clin Endocrinol Metab. 1968 May;28(5):714–716. doi: 10.1210/jcem-28-5-714. [DOI] [PubMed] [Google Scholar]
  8. Galbo H., Hummer L., Peterson I. B., Christensen N. J., Bie N. Thyroid and testicular hormone responses to graded and prolonged exercise in man. Eur J Appl Physiol Occup Physiol. 1977 Jan 14;36(2):101–106. doi: 10.1007/BF00423117. [DOI] [PubMed] [Google Scholar]
  9. Johannessen A., Hagen C., Galbo H. Prolactin, growth hormone, thyrotropin, 3,5,3'-triiodothyronine, and thyroxine responses to exercise after fat- and carbohydrate-enriched diet. J Clin Endocrinol Metab. 1981 Jan;52(1):56–61. doi: 10.1210/jcem-52-1-56. [DOI] [PubMed] [Google Scholar]
  10. Melander A., Ericson L. E., Ljunggren J. G., Norberg K. A., Persson B., Sundler F., Tibblin S., Westgren U. Sympathetic innervation of the normal human thyroid. J Clin Endocrinol Metab. 1974 Oct;39(4):713–718. doi: 10.1210/jcem-39-4-713. [DOI] [PubMed] [Google Scholar]
  11. Melander A., Ranklev E., Sundler F., Westgren U. Beta2-adrenergic stimulation of thyroid hormone secretion. Endocrinology. 1975 Aug;97(2):332–336. doi: 10.1210/endo-97-2-332. [DOI] [PubMed] [Google Scholar]
  12. Métivier G., Gauthier R. The effects of acute exercise on the level of blood serum tri-iodothyronine (T3), thyroxine (T4) and free thyroxine index (FTI) in the aging male. J Sports Med Phys Fitness. 1981 Dec;21(4):371–376. [PubMed] [Google Scholar]
  13. O'Connell M., Robbins D. C., Horton E. S., Sims E. A., Danforth E., Jr Changes in serum concentrations of 3,3',5'-triiodothyronine and 3,5,3'-triiodothyronine during prolonged moderate exercise. J Clin Endocrinol Metab. 1979 Aug;49(2):242–246. doi: 10.1210/jcem-49-2-242. [DOI] [PubMed] [Google Scholar]
  14. Premachandra B. N., Winder W. W., Hickson R., Lang S., Holloszy J. O. Circulating reverse triiodothyronine in humans during exercise. Eur J Appl Physiol Occup Physiol. 1981;47(3):281–288. doi: 10.1007/BF00422473. [DOI] [PubMed] [Google Scholar]
  15. Rosenfeld L. "Free thyroxine index". A reliable substitute for "free" thyroxine concentration. Am J Clin Pathol. 1974 Jan;61(1):118–121. doi: 10.1093/ajcp/61.1.118. [DOI] [PubMed] [Google Scholar]
  16. Schmid P., Wolf W., Pilger E., Schwaberger G., Pessenhofer H., Pristautz H., Leb G. TSH, T3, rT3 and fT4 in maximal and submaximal physical exercise. Eur J Appl Physiol Occup Physiol. 1982;48(1):31–39. doi: 10.1007/BF00421162. [DOI] [PubMed] [Google Scholar]
  17. Sowers J. R., Raj R. P., Hershman J. M., Carlson H. E., McCallum R. W. The effect of stressful diagnostic studies and surgery on anterior pituitary hormone release in man. Acta Endocrinol (Copenh) 1977 Sep;86(1):25–32. doi: 10.1530/acta.0.0860025. [DOI] [PubMed] [Google Scholar]
  18. Terjung R. L., Tipton C. M. Plasma thyroxine and thyroid-stimulating hormone levels during submaximal exercise in humans. Am J Physiol. 1971 Jun;220(6):1840–1845. doi: 10.1152/ajplegacy.1971.220.6.1840. [DOI] [PubMed] [Google Scholar]
  19. Terjung R. L., Winder W. W. Exercise and thyroid function. Med Sci Sports. 1975 Spring;7(1):20–26. [PubMed] [Google Scholar]
  20. Vagenakis A. G., Burger A., Portnary G. I., Rudolph M., O'Brian J. R., Azizi F., Arky R. A., Nicod P., Ingbar S. H., Braverman L. E. Diversion of peripheral thyroxine metabolism from activating to inactivating pathways during complete fasting. J Clin Endocrinol Metab. 1975 Jul;41(1):191–194. doi: 10.1210/jcem-41-1-191. [DOI] [PubMed] [Google Scholar]

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