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. 1983 Nov;24(5):803–806. doi: 10.1128/aac.24.5.803

Effects of (E)-5-(2-bromovinyl)-2'-deoxyuridine on proliferation of human fibroblasts, peripheral blood mononuclear cells, and granulocyte-monocyte progenitor cells in vitro.

A E Wittek, P S Cohen, A M Arvin, S D Smith, C M Koropchak, E De Clercq
PMCID: PMC185945  PMID: 6660853

Abstract

Inhibition of human fibroblasts, granulocyte-monocyte progenitor cells, and lymphocytes was observed at (E)-5-(2-bromovinyl)-2'-deoxyuridine concentrations ranging from 21 to 197 micrograms/ml. These concentrations were 10- to 100-fold above usual serum concentrations after oral administration. (E)-5-(2-Bromovinyl)-2'-deoxyuridine compares favorably with currently used antivirals in terms of in vitro myelotoxicity and immunotoxicity.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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