Table 1 Comparison of blood parameters between patients with and without brain magnetic resonance imaging (MRI) abnormalities and control subjects.
| Abnormal MRI (n = 7) | Normal MRI (n = 8) | Control subjects (n = 9) | p Value | |
|---|---|---|---|---|
| Age (years) | 26.3 (10) | 23.4 (6.5) | 23.1 (5.8) | 0.574 |
| Oxygen saturation (%) | 77.9 (5.8)*** †† | 88.0 (6.6)* | 96.4 (1.3) | <0.001 |
| Packed cell volume (%) | 63.2 (7.6)*** † | 54.3 (7.3)** | 42.4 (2.2) | 0.016 |
| MCV (fl) | 94.6 (9.2) | 96.8 (6.1) | 93.2 (2.9) | 0.971 |
| Platelet count (×109/l) | 173 (44) | 181 (64) | 249 (79) | 0.053 |
| Soluble P selectin (ng/ml) | 105 (38) | 77.7 (36) | 68.7 (24) | 0.100 |
| Prothrombin time (%) | 76.3 (12) | 81.6 (9.8) | 92.2 (15) | 0.118 |
| APTT (s) | 37.1 (4.8) | 38.1 (3.3) | 38.9 (3.3) | 0.560 |
| Fibrinogen (μmol/l) | 9.0 (2.6) | 9.06 (2.9) | 7.79 (1.9) | 0.418 |
| Antithrombin III (%) | 92.1 (19) | 92.3 (11) | 108 (9.6) | 0.306 |
| TAT (ng/ml) | 1.79 (1.2) | 1.18 (0.26) | 1.20 (0.25) | 0.520 |
| Thrombomodulin (ng/ml) | 18.3 (8.6) | 15.7 (5.3) | 23.6 (5.1) | 0.689 |
| Protein C activity (%) | 65.6 (15.9)** † | 88.7 (3.4) | 100 (21) | 0.002 |
| Protein S antigen (%) | 76.0 (12) | 76.3 (20) | 90.7 (15) | 0.199 |
| PAI‐1 antigen (ng/ml) | 6.0 (3.6) | 9.5 (4.5) | 6.3 (3.7) | 0.338 |
Data are mean (SD).
p<0.05 is considered significant (analysis of variance).
Scheffe post hoc test: *p<0.02, **p<0.005, ***p<0.001 v control; †p<0.05, ††p<0.005 v normal MRI.
APTT, activated partial thromboplastin time; MCV, mean corpuscular volume; PAI‐1, plasminogen activator inhibitor 1; TAT, thrombin‐antithrombin complex.