Table 1 Baseline characteristics of 268 patients with Marfan's syndrome.
| No dissection or aortic repair (n = 189) | Elective aortic repair (n = 53) | Dissection (type B: n = 2) (n = 26) | p Value* | ||
|---|---|---|---|---|---|
| Age (years) | 30 (11) | 36 (13) | 35 (10) | ||
| Women (n = 139) | 60% | 32% | 39% | ||
| Ever pregnant (n/m)** | 48% (53/110) | 31% (5/16) | 44% (4/9) | ||
| Mutations | |||||
| Yes | 52 | 12 | 8 | ||
| No | 60 | 19 | 5 | ||
| Unknown | 74 | 21 | 13 | ||
| Mitral valve intervention | 3 (2%) | 6 (11%) | 1 (4%) | ||
| Arrhythmias | 17 (9%)) | 6 (11%) | 5 (19%) | ||
| β blockers | 94 (50%) | 28 (53%) | 16 (62%) | ||
| Aortic diameter (mm) | |||||
| Root | n = 182† | 40 (36–45) | NA | ||
| Arch | n = 112,18,13† | 24 (22–27) | 26 (24–30)‡ | 27 (23–41)§ | 0.014 |
| Descending | n = 83,15,11† | 20 (18–22) | 25 (20–28)‡ | 30 (26–42)§ | 0.003 |
| Abdominal | n = 76,21,11† | 17 (15–19) | 20 (18–23)‡ | 30 (27–40)§ | 0.003 |
Age is reported as mean (SD); aortic dimensions as medians (interquartile range).
*Patients without dissection or aortic repair compared with patients with an elective aortic repair; †numbers of patients in each of the groups for whom data were available, enumerated in the same order as the columns of the table: no dissection, elective surgery, dissection; ‡patients who had undergone an aortic intervention in another part than the root (n = 6) were excluded in calculating these averages; §one patient who had undergone surgery of the distal aorta was excluded; **The denominator “m” refers to the numbers of patients for whom data on pregnancy were available.