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. 1994 Feb;62(2):700–703. doi: 10.1128/iai.62.2.700-703.1994

Acquisition of heme iron by Neisseria meningitidis does not involve meningococcal transferrin-binding proteins.

N Martel 1, B C Lee 1
PMCID: PMC186161  PMID: 8300227

Abstract

Similarities in size between hemin-binding protein 1 (HmBP1) and transferrin-binding protein 1 (TBP1) of Neisseria meningitidis suggest that these proteins are functionally homologous. However, a meningococcal mutant lacking the transferrin-binding proteins retained the capacity to acquire iron from heme and hemoglobin. In immunoblots, hyperimmune polyclonal antiserum against TBP1 did not react with HmBP1.

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Selected References

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