Skip to main content
Canadian Medical Association Journal logoLink to Canadian Medical Association Journal
. 1982 Oct 1;127(7):606–607.

Effets immédiats du dimenhydrinate sur la contraction utérine e le rythme cardiaque foetal durant le travail.

Immediate effects of dimenhydrinate on uterine contraction and the fetal cardiac rhythm during labor

M Lemay, M Samaan, P St Michel, L Granger, R Pigeon
PMCID: PMC1862164  PMID: 7127229

Abstract

The effects of intravenous administration of 100 mg of dimenhydrinate (Gravol) were studied in 20 patients during active spontaneous labour. The uterine activity and the fetal heart rate were monitored by an invasive technique. After administration of the medication the uterine activity increases significantly, and in 20% of the cases decelerations in the fetal heart rate of the hypoxic type occurred. Because of its unpredictable effects, this drug should be used with care during labour.

Full text

PDF
606

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. COOPER K. FAILURE OF DIMENHYDRINATE TO SHORTEN LABOR. Am J Obstet Gynecol. 1963 Aug 15;86:1041–1043. doi: 10.1016/s0002-9378(16)35291-7. [DOI] [PubMed] [Google Scholar]
  2. Hay T. B., Wood C. The effect of dimenhydrinate on uterine contractions. Aust N Z J Obstet Gynaecol. 1967 May;7(2):81–89. doi: 10.1111/j.1479-828x.1967.tb02493.x. [DOI] [PubMed] [Google Scholar]
  3. KLIEGER J. A., MASSART J. J. CLINICAL AND LABORATORY SURVEY INTO THE OXYTOCIC EFFECTS OF DIMENHYDRINATE IN LABOR. Am J Obstet Gynecol. 1965 May 1;92:1–10. doi: 10.1016/0002-9378(65)90098-0. [DOI] [PubMed] [Google Scholar]
  4. ROTTER C. W., WHITAKER J. L., YARED J. The use of intravenous dramamine to shorten the time of labor and potentiate analgesia. Am J Obstet Gynecol. 1958 May;75(5):1101–1104. doi: 10.1016/0002-9378(58)90832-9. [DOI] [PubMed] [Google Scholar]
  5. SCOTT R. S. THE USE OF INTRAVENOUS DIMENHYDRINATE IN LABOR. New Physician. 1964 Sep;13:302–307. [PubMed] [Google Scholar]
  6. SCOTT R. S., WALLACE K. H., BADLEY D. N., WATSON B. H. Use of dimenhydrinate in labor. Am J Obstet Gynecol. 1962 Jan 1;83:25–28. doi: 10.1016/0002-9378(62)90283-1. [DOI] [PubMed] [Google Scholar]
  7. Shephard B., Cruz A., Spellacy W. The acute effects of Dramamine on uterine contractability during labor. J Reprod Med. 1976 Jan;16(1):27–28. [PubMed] [Google Scholar]

Articles from Canadian Medical Association Journal are provided here courtesy of Canadian Medical Association

RESOURCES