Abstract
This paper contains discussion of a number of mechanisms which may explain the suppression of the cell-mediated immune response during the phase of dissemination of mycobacterial infection in mice and men. However, it is not yet possible to evaluate the relative importance of these mechanisms, or even to say which are the causes and which are the consequences of that disseminaton.
Full text
PDF


Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bryceson A. D., Bray R. S., Dumonde D. C. Experimental cutaneous leishmaniasis. IV. Selective suppression of cell-mediated immunity during the response of guinea-pigs to infection with Leishmania enriettii. Clin Exp Immunol. 1974 Feb;16(2):189–202. [PMC free article] [PubMed] [Google Scholar]
- Calderon J., Unanue E. R. Two biological activities regulating cell proliferation found in cultures of peritoneal exudate cells. Nature. 1975 Jan 31;253(5490):359–361. doi: 10.1038/253359a0. [DOI] [PubMed] [Google Scholar]
- Gery I., Gershon R. K., Waksman B. H. Potentiation of the T-lymphocyte response to mitogens. I. The responding cell. J Exp Med. 1972 Jul 1;136(1):128–142. doi: 10.1084/jem.136.1.128. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Keller R. Major changes in lymphocyte proliferation evoked by activated macrophages. Cell Immunol. 1975 Jun;17(2):542–551. doi: 10.1016/s0008-8749(75)80058-x. [DOI] [PubMed] [Google Scholar]
- Lederer E., Adam A., Ciorbaru R., Petit J. F., Wietzerbin J. Cell walls of Mycobacteria and related organisms; chemistry and immunostimulant properties. Mol Cell Biochem. 1975 May 30;7(2):87–104. doi: 10.1007/BF01792076. [DOI] [PubMed] [Google Scholar]
- Mackaness G. B., Lagrange P. H., Miller T. E., Ishibashi T. Feedback inhibition of specifically sensitized lymphocytes. J Exp Med. 1974 Mar 1;139(3):543–559. doi: 10.1084/jem.139.3.543. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Mokyr M. B., Mitchell M. S. Activation of lymphoid cells by BCG in vitro. Cell Immunol. 1975 Feb;15(2):264–273. doi: 10.1016/0008-8749(75)90005-2. [DOI] [PubMed] [Google Scholar]
- Myrvang B., Godal T., Ridley D. S., Fröland S. S., Song Y. K. Immune responsiveness to Mycobacterium leprae and other mycobacterial antigens throughout the clinical and histopathological spectrum of leprosy. Clin Exp Immunol. 1973 Aug;14(4):541–553. [PMC free article] [PubMed] [Google Scholar]
- Nelson D. S., Penrose J. M., Waters M. F., Pearson J. M., Nelson M. Depressive effect of serum from patients with leprosy on mixed lymphocyte reactions. Influence of anti-leprosy treatment. Clin Exp Immunol. 1975 Dec;22(3):385–392. [PMC free article] [PubMed] [Google Scholar]
- Ridley D. S., Jopling W. H. Classification of leprosy according to immunity. A five-group system. Int J Lepr Other Mycobact Dis. 1966 Jul-Sep;34(3):255–273. [PubMed] [Google Scholar]
- Schlossman S. F., Levin H. A., Rocklin R. E., David J. R. The compartmentalization of antigen-reactive lymphocytes in desensitized guinea pigs. J Exp Med. 1971 Sep 1;134(3 Pt 1):741–750. doi: 10.1084/jem.134.3.741. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Watson S. R., Sljivić V. S., Brown I. N. Defect of macrophage function in the antibody response to sheep erythrocytes in systemic Mycobacterium lepraemurium infection. Nature. 1975 Jul 17;256(5514):206–208. doi: 10.1038/256206b0. [DOI] [PubMed] [Google Scholar]