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. 1994 May;62(5):2094–2097. doi: 10.1128/iai.62.5.2094-2097.1994

Intravaginal inoculation of mice with the Chlamydia trachomatis mouse pneumonitis biovar results in infertility.

L M de la Maza 1, S Pal 1, A Khamesipour 1, E M Peterson 1
PMCID: PMC186471  PMID: 8168974

Abstract

In an attempt to establish a model of chlamydial ascending salpingitis and infertility, three inbred strains of mice, C3H/HeN (H-2k), C57BL/6N (H-2b), and BALB/cAnN (H-2d), were inoculated intravaginally with 3 x 10(7) inclusion-forming units of the Chlamydia trachomatis mouse pneumonitis biovar. Mice mated 6 weeks following inoculation were found to have a significant decrease in fertility rate compared with the control groups, as shown by a reduction in the number of pregnant mice and a decrease in the number of embryos.

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Selected References

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