Abstract
Sexual morphogenesis in Achlya, a filamentous water mold, is initiated by two hormones. Hormone A, or antheridiol, is a C-29 steroid. Four stereoisomers of antheridiol have been synthesized. The natural one (antheridiol 22S 23R) and its 7-deoxy 7-dihydro form, when added to an aerated culture of hermaphroditic Achlya heterosexualis, stimulated this mold to secrete twice as much hormone B as the untreated control. An unnatural stereoisomer (antheridiol 22R 23S) and fucosterol, however, did not stimulate strain 8-6 in the same way. Methods by which hormone B can be produced in sufficient yield for isolation and characterization are described.
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Selected References
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- McMorris T. C., Barksdale A. W. Isolation of a sex hormone from the water mould Achlya bisexualis. Nature. 1967 Jul 15;215(5098):320–321. doi: 10.1038/215320a0. [DOI] [PubMed] [Google Scholar]