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. 2002 May;50(Suppl 4):iv13–iv16. doi: 10.1136/gut.50.suppl_4.iv13

Role of endoscopy and biopsy in the work up of dyspepsia

G Tytgat
PMCID: PMC1867697  PMID: 11953339

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Adang R. P., Vismans J. F., Talmon J. L., Hasman A., Ambergen A. W., Stockbrügger R. W. Appropriateness of indications for diagnostic upper gastrointestinal endoscopy: association with relevant endoscopic disease. Gastrointest Endosc. 1995 Nov;42(5):390–397. doi: 10.1016/s0016-5107(95)70037-4. [DOI] [PubMed] [Google Scholar]
  2. Allison M. C., Howatson A. G., Torrance C. J., Lee F. D., Russell R. I. Gastrointestinal damage associated with the use of nonsteroidal antiinflammatory drugs. N Engl J Med. 1992 Sep 10;327(11):749–754. doi: 10.1056/NEJM199209103271101. [DOI] [PubMed] [Google Scholar]
  3. Axon A. Which patients should be referred for open-access endoscopy? Endoscopy. 1996 Oct;28(8):722–723. doi: 10.1055/s-2007-1005584. [DOI] [PubMed] [Google Scholar]
  4. Beavis A. K., La Brooy S., Misiewicz J. J. Evaluation of one-visit endoscopic clinic for patients with dyspepsia. Br Med J. 1979 May 26;1(6175):1387–1389. doi: 10.1136/bmj.1.6175.1387. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Bernersen B., Johnsen R., Straume B., Burhol P. G., Jenssen T. G., Stakkevold P. A. Towards a true prevalence of peptic ulcer: the Sørreisa gastrointestinal disorder study. Gut. 1990 Sep;31(9):989–992. doi: 10.1136/gut.31.9.989. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Bytzer P., Hansen J. M., Schaffalitzky de Muckadell O. B. Empirical H2-blocker therapy or prompt endoscopy in management of dyspepsia. Lancet. 1994 Apr 2;343(8901):811–816. doi: 10.1016/s0140-6736(94)92023-0. [DOI] [PubMed] [Google Scholar]
  7. Carpenter H. A., Talley N. J. Gastroscopy is incomplete without biopsy: clinical relevance of distinguishing gastropathy from gastritis. Gastroenterology. 1995 Mar;108(3):917–924. doi: 10.1016/0016-5085(95)90468-9. [DOI] [PubMed] [Google Scholar]
  8. Crean G. P., Holden R. J., Knill-Jones R. P., Beattie A. D., James W. B., Marjoribanks F. M., Spiegelhalter D. J. A database on dyspepsia. Gut. 1994 Feb;35(2):191–202. doi: 10.1136/gut.35.2.191. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Dixon M. F., Genta R. M., Yardley J. H., Correa P. Classification and grading of gastritis. The updated Sydney System. International Workshop on the Histopathology of Gastritis, Houston 1994. Am J Surg Pathol. 1996 Oct;20(10):1161–1181. doi: 10.1097/00000478-199610000-00001. [DOI] [PubMed] [Google Scholar]
  10. Edenholm M., Gustavsson R., Jansson O., Lingfors H., Nilsson O., Söderlind T., Titusson L., Thulin A. Endoscopic findings in patients with ulcer-like dyspepsia. Scand J Gastroenterol Suppl. 1985;109:163–167. doi: 10.3109/00365528509103953. [DOI] [PubMed] [Google Scholar]
  11. Fjøsne U., Kleveland P. M., Waldum H., Halvorsen T., Petersen H. The clinical benefit of routine upper gastrointestinal endoscopy. Scand J Gastroenterol. 1986 May;21(4):433–440. doi: 10.3109/00365528609015159. [DOI] [PubMed] [Google Scholar]
  12. Gear M. W., Barnes R. J. Endoscopic studies of dyspepsia in a general practice. Br Med J. 1980 May 3;280(6223):1136–1137. doi: 10.1136/bmj.280.6223.1136. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. Gonvers J. J., Burnand B., Froehlich F., Pache I., Thorens J., Fried M., Kosecoff J., Vader J. P., Brook R. H. Appropriateness and diagnostic yield of upper gastrointestinal endoscopy in an open-access endoscopy unit. Endoscopy. 1996 Oct;28(8):661–666. doi: 10.1055/s-2007-1005573. [DOI] [PubMed] [Google Scholar]
  14. Hallissey M. T., Allum W. H., Jewkes A. J., Ellis D. J., Fielding J. W. Early detection of gastric cancer. BMJ. 1990 Sep 15;301(6751):513–515. doi: 10.1136/bmj.301.6751.513. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Heikkinen M., Pikkarainen P., Takala J., Räsänen H., Julkunen R. Etiology of dyspepsia: four hundred unselected consecutive patients in general practice. Scand J Gastroenterol. 1995 Jun;30(6):519–523. doi: 10.3109/00365529509089783. [DOI] [PubMed] [Google Scholar]
  16. Hu P. J., Li Y. Y., Zhou M. H., Chen M. H., Du G. G., Huang B. J., Mitchell H. M., Hazell S. L. Helicobacter pylori associated with a high prevalence of duodenal ulcer disease and a low prevalence of gastric cancer in a developing nation. Gut. 1995 Feb;36(2):198–202. doi: 10.1136/gut.36.2.198. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Johannessen T., Petersen H., Kleveland P. M., Dybdahl J. H., Sandvik A. K., Brenna E., Waldum H. The predictive value of history in dyspepsia. Scand J Gastroenterol. 1990 Jul;25(7):689–697. doi: 10.3109/00365529008997594. [DOI] [PubMed] [Google Scholar]
  18. Johnsen R., Bernersen B., Straume B., Førde O. H., Bostad L., Burhol P. G. Prevalences of endoscopic and histological findings in subjects with and without dyspepsia. BMJ. 1991 Mar 30;302(6779):749–752. doi: 10.1136/bmj.302.6779.749. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Kagevi I., Löfstedt S., Persson L. G. Endoscopic findings and diagnoses in unselected dyspeptic patients at a primary health care center. Scand J Gastroenterol. 1989 Mar;24(2):145–150. doi: 10.3109/00365528909093029. [DOI] [PubMed] [Google Scholar]
  20. Kerrigan D. D., Brown S. R., Hutchinson G. H. Open access gastroscopy: too much to swallow? BMJ. 1990 Feb 10;300(6721):374–376. doi: 10.1136/bmj.300.6721.374. [DOI] [PMC free article] [PubMed] [Google Scholar]
  21. Klauser A. G., Voderholzer W. A., Knesewitsch P. A., Schindlbeck N. E., Müller-Lissner S. A. What is behind dyspepsia? Dig Dis Sci. 1993 Jan;38(1):147–154. doi: 10.1007/BF01296788. [DOI] [PubMed] [Google Scholar]
  22. Lanza F. L., Codispoti J. R., Nelson E. B. An endoscopic comparison of gastroduodenal injury with over-the-counter doses of ketoprofen and acetaminophen. Am J Gastroenterol. 1998 Jul;93(7):1051–1054. doi: 10.1111/j.1572-0241.1998.00327.x. [DOI] [PubMed] [Google Scholar]
  23. Lee M., Cryer B., Feldman M. Dose effects of aspirin on gastric prostaglandins and stomach mucosal injury. Ann Intern Med. 1994 Feb 1;120(3):184–189. doi: 10.7326/0003-4819-120-3-199402010-00002. [DOI] [PubMed] [Google Scholar]
  24. Mansi C., Savarino V., Mela G. S., Picciotto A., Mele M. R., Celle G. Are clinical patterns of dyspepsia a valid guideline for appropriate use of endoscopy? A report on 2253 dyspeptic patients. Am J Gastroenterol. 1993 Jul;88(7):1011–1015. [PubMed] [Google Scholar]
  25. McColl K. E., el-Nujumi A., Murray L. S., el-Omar E. M., Dickson A., Kelman A. W., Hilditch T. E. Assessment of symptomatic response as predictor of Helicobacter pylori status following eradication therapy in patients with ulcer. Gut. 1998 May;42(5):618–622. doi: 10.1136/gut.42.5.618. [DOI] [PMC free article] [PubMed] [Google Scholar]
  26. Quine M. A., Bell G. D., McCloy R. F., Devlin H. B., Hopkins A. Appropriate use of upper gastrointestinal endoscopy--a prospective audit. Steering Group of the Upper Gastrointestinal Endoscopy Audit Committee. Gut. 1994 Sep;35(9):1209–1214. doi: 10.1136/gut.35.9.1209. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. Sipponen P., Stolte M. Clinical impact of routine biopsies of the gastric antrum and body. Endoscopy. 1997 Sep;29(7):671–678. doi: 10.1055/s-2007-1004278. [DOI] [PubMed] [Google Scholar]
  28. Sobala G. M., Crabtree J. E., Pentith J. A., Rathbone B. J., Shallcross T. M., Wyatt J. I., Dixon M. F., Heatley R. V., Axon A. T. Screening dyspepsia by serology to Helicobacter pylori. Lancet. 1991 Jul 13;338(8759):94–96. doi: 10.1016/0140-6736(91)90085-4. [DOI] [PubMed] [Google Scholar]
  29. Talley N. J., Stanghellini V., Heading R. C., Koch K. L., Malagelada J. R., Tytgat G. N. Functional gastroduodenal disorders. Gut. 1999 Sep;45 (Suppl 2):II37–II42. doi: 10.1136/gut.45.2008.ii37. [DOI] [PMC free article] [PubMed] [Google Scholar]
  30. Talley N. J., Zinsmeister A. R., Schleck C. D., Melton L. J., 3rd Dyspepsia and dyspepsia subgroups: a population-based study. Gastroenterology. 1992 Apr;102(4 Pt 1):1259–1268. [PubMed] [Google Scholar]
  31. Wiklund I., Glise H., Jerndal P., Carlsson J., Talley N. J. Does endoscopy have a positive impact on quality of life in dyspepsia? Gastrointest Endosc. 1998 Jun;47(6):449–454. doi: 10.1016/s0016-5107(98)70243-3. [DOI] [PubMed] [Google Scholar]
  32. Williams B., Luckas M., Ellingham J. H., Dain A., Wicks A. C. Do young patients with dyspepsia need investigation? Lancet. 1988 Dec 10;2(8624):1349–1351. doi: 10.1016/s0140-6736(88)90879-3. [DOI] [PubMed] [Google Scholar]
  33. Zaman A., Hapke R., Sahagun G., Katon R. M. Unsedated peroral endoscopy with a video ultrathin endoscope: patient acceptance, tolerance, and diagnostic accuracy. Am J Gastroenterol. 1998 Aug;93(8):1260–1263. doi: 10.1111/j.1572-0241.1998.00406.x. [DOI] [PubMed] [Google Scholar]

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