Abstract
Distribution of trace element levels in corn germ fractions from kernels naturally infected with Aspergillus flavus and from kernels free of the fungus demonstrated an association between the presence of A. flavus and higher levels of metals. A. flavus production of aflatoxin on various autoclaved corn media showed that ground, whole corn was an excellent substrate; similar high levels of toxin were observed on full-fat corn germ but endosperm and defatted corn germ supported reduced yields. The influence of trace elements and their availability in defatted corn germ to A. flavus-mediated aflatoxin biosynthesis were measured. Enrichment of the substrate with 5 to 10 μg of manganese, copper, cadmium, or chromium per g of germ increased toxin yields. Addition of lead or zinc (50 to 250 μg/g) also enhanced toxin accumulation. Aflatoxin elaboration was reduced by the addition of 25 μg of cadmium per g or 500 μg of copper per g of germ.
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- ADYE J., MATELES R. I. INCORPORATION OF LABELLED COMPOUNDS INTO AFLATOXINS. Biochim Biophys Acta. 1964 May 11;86:418–420. doi: 10.1016/0304-4165(64)90077-7. [DOI] [PubMed] [Google Scholar]
- Dantzman J., Stoloff L. Screening method for aflatoxin in corn and various corn products. J Assoc Off Anal Chem. 1972 Jan;55(1):139–141. [PubMed] [Google Scholar]
- Davis N. D., Diener U. L., Agnihotri V. P. Production of aflatoxins B1 and G1 in chemically defined medium. Mycopathol Mycol Appl. 1967 Apr 28;31(3):251–256. doi: 10.1007/BF02053422. [DOI] [PubMed] [Google Scholar]
- MATELES R. I., ADYE J. C. PRODUCTION OF AFLATOXINS IN SUBMERGED CULTURE. Appl Microbiol. 1965 Mar;13:208–211. doi: 10.1128/am.13.2.208-211.1965. [DOI] [PMC free article] [PubMed] [Google Scholar]
- O'Dell B. L., Burpo C. E., Savage J. E. Evaluation of zinc availability in foodstuffs of plant and animal origin. J Nutr. 1972 May;102(5):653–660. doi: 10.1093/jn/102.5.653. [DOI] [PubMed] [Google Scholar]
- Schroeder H. W. Effect of corn steep liquor on mycelial growth and aflatoxin production in Aspergillus parasiticus. Appl Microbiol. 1966 May;14(3):381–385. doi: 10.1128/am.14.3.381-385.1966. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Zicot M., Boland J. Sur certains paramètres hémodynamiques, continus et pulsatilis, des poumons isolés de lapin. C R Seances Soc Biol Fil. 1972;166(4):718–721. [PubMed] [Google Scholar]