Abstract
A survey of the 38 patients resident in Ontario from whose sputum, body fluids or tissues Blastomyces dermatitidis was cultured by our laboratory between 1970 and 1981 revealed a new endemic focus to the north and east of Lake Superior, where 20 of 27 traceable patients lived. Direct microscopy revealed B. dermatitidis in 90% of the cases. A lack of clinical awareness, however, had often resulted in a delay (average 15 weeks) in diagnosis. In two cases the disease was identified only at autopsy. About 80% of the patients survived.
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- Ajello L. A comparative study of the pulmonary mycoses of Canada and the United States. Public Health Rep. 1969 Oct;84(10):869–877. [PMC free article] [PubMed] [Google Scholar]
- Denton J. F., DiSalvo A. F. Additional isolations of Blastomyces dermatitidis from natural sites. Am J Trop Med Hyg. 1979 Jul;28(4):697–700. [PubMed] [Google Scholar]
- Duttera M. J., Jr, Osterhout S. North American blastomycosis: a survey of 63 cases. South Med J. 1969 Mar;62(3):295–301. [PubMed] [Google Scholar]
- Fishcer J. B., Kane J. The laboratory diagnosis of dermatophytosis complicated with Candida albicans. Can J Microbiol. 1974 Feb;20(2):167–182. doi: 10.1139/m74-027. [DOI] [PubMed] [Google Scholar]
- Kane J., Blakeman J. M., Fischer J. B. Tinea cruris: diagnostic confusion due to isolation of Candida albicans alone. Can Med Assoc J. 1976 May 8;114(9):797–798. [PMC free article] [PubMed] [Google Scholar]
- Kaufman L., McLaughlin D. W., Clark M. J., Blumer S. Specific immunodiffusion test for blastomycosis. Appl Microbiol. 1973 Sep;26(3):244–247. doi: 10.1128/am.26.3.244-247.1973. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kepron M. W., Schoemperlen, Hershfield E. S., Zylak C. J., Cherniack R. M. North American blastomycosis in Central Canada. A review of 36 cases. Can Med Assoc J. 1972 Feb 5;106(3):243–246. [PMC free article] [PubMed] [Google Scholar]
- Kitchen M. S., Reiber C. D., Eastin G. B. An urban epidemic of North American blastomycosis. Am Rev Respir Dis. 1977 Jun;115(6):1063–1066. doi: 10.1164/arrd.1977.115.6.1063. [DOI] [PubMed] [Google Scholar]
- MCDONOUGH E. S., VANPROOIEN R., LEWIS A. L. LYSIS OF BLASTOMYCES DERMATITIDIS YEAST-PHASE CELLS IN NATURAL SOIL. Am J Epidemiol. 1965 Jan;81:86–94. doi: 10.1093/oxfordjournals.aje.a120500. [DOI] [PubMed] [Google Scholar]
- Macher A. Histoplasmosis and blastomycosis. Med Clin North Am. 1980 May;64(3):447–459. doi: 10.1016/s0025-7125(16)31603-0. [DOI] [PubMed] [Google Scholar]
- McDonough E. S., Dubats J. J., Wisniewski T. R., Wallenfang M. A., McNamara W. J. Soil streptomycetes and bacteria related to lysis of Blastomyces dermatitidis. Sabouraudia. 1973 Nov;11(3):244–250. doi: 10.1080/00362177385190491. [DOI] [PubMed] [Google Scholar]
- O'Neill R. P., Penman R. W. Clinical aspects of blastomycosis. Thorax. 1970 Nov;25(6):708–715. doi: 10.1136/thx.25.6.708. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Sarosi G. A., Davies S. F. Blastomycosis. Am Rev Respir Dis. 1979 Oct;120(4):911–938. doi: 10.1164/arrd.1979.120.4.911. [DOI] [PubMed] [Google Scholar]
- Sekhon A. S., Bogorus M. S., Sims H. V. Blastomycosis: report of three cases from Alberta with a review of Canadian cases. Mycopathologia. 1979 Aug 31;68(1):53–63. doi: 10.1007/BF00490391. [DOI] [PubMed] [Google Scholar]
- Tosh F. E., Hammerman K. J., Weeks R. J., Sarosi G. A. A common source epidemic of North American blastomycosis. Am Rev Respir Dis. 1974 May;109(5):525–529. doi: 10.1164/arrd.1974.109.5.525. [DOI] [PubMed] [Google Scholar]
- Witorsch P., Utz J. P. North American blastomycosis: a study of 40 patients. Medicine (Baltimore) 1968 May;47(3):169–200. doi: 10.1097/00005792-196805000-00001. [DOI] [PubMed] [Google Scholar]